Rabbit GPR162 Polyclonal Antibody | anti-GPR162 antibody

Rabbit Polyclonal to Human GPR162

Cat. Num. AAA243225

• Gene Names: GPR162; A-2; GRCA
• Reactivity: Gibbon, Human, Mouse; Predicted Reactivity: Monkey, Hamster, Pig (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: GPR162; Polyclonal Antibody; Rabbit Polyclonal to Human GPR162; Anti-GPR162 Antibody (Extracellular Domain) IHC-plus; A-2; Gene rich cluster; A; G protein-coupled receptor 162; GRCA; Human GPR162; anti-GPR162 antibody

• Host: Rabbit
• Reactivity: Gibbon, Human, Mouse; Predicted Reactivity: Monkey, Hamster, Pig (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human GPR162. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MADD (72%).
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 588

• Applicable Applications for anti-GPR162 antibody: Immunohistochemistry (IHC - Paraffin)
• Application Notes: IHC-P (7 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic 18 amino acid peptide from 2nd extracellular domain of human GPR162. Percent identity with other species by BLAST analysis: Human, Gibbon, Mouse (100%); Monkey, Hamster, Pig (94%); Dog, Horse (89%); Rat, Bovine, Panda (83%).
• Immunogen Type: Synthetic peptide
• Immunogen: GPR162 antibody was raised against synthetic 18 amino acid peptide from 2nd extracellular domain of human GPR162. Percent identity with other species by BLAST analysis: Human, Gibbon, Mouse (100%); Monkey, Hamster, Pig (94%); Dog, Horse (89%); Rat, Bovine, Panda (83%).
• Antigen Modification: Extracellular Domain
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-GPR162 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GPR162 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GPR162 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-GPR162 antibody

Protein A is an Orphan-U GPCR with an unknown ligand. This gene was identified from genomic analysis of a gene-dense region at human chromosome 12p13. It appears to be expressed mainly in the brain. However, its function is not known. Three alternatively spliced variants have been described; the full length of the third variant is yet to be determined.

Product Categories/Family for anti-GPR162 antibody

Family: GPCR; Subfamily: Orphan-U

NCBI and Uniprot Product Information

• NCBI GI #: 9951913
• NCBI GeneID: 27239
• NCBI Accession #: NP_062832.1
• NCBI GenBank Nucleotide #: NM_019858.1
• UniProt Accession #: Q16538; Q16664; Q59EH5; Q66K56
• Molecular Weight: 33,062 Da
• NCBI Official Full Name: probable G-protein coupled receptor 162 isoform 2
• NCBI Official Synonym Full Names: G protein-coupled receptor 162
• NCBI Official Symbol: GPR162
• NCBI Official Synonym Symbols: A-2; GRCA
• NCBI Protein Information: probable G-protein coupled receptor 162; gene rich cluster, A; gene-rich cluster gene A protein
• UniProt Protein Name: Probable G-protein coupled receptor 162
• Protein Family: Probable G-protein coupled receptor
• UniProt Gene Name: GPR162
• UniProt Synonym Gene Names: GRCA
• UniProt Entry Name: GP162_HUMAN

NCBI Description

This gene was identified upon genomic analysis of a gene-dense region at human chromosome 12p13. It appears to be mainly expressed in the brain; however, its function is not known. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

GPR162: Orphan receptor. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway