Rabbit anti-Human, Mouse GPR132 Polyclonal Antibody | anti-GPR132 antibody

GPR132 Antibody

Cat. Num. AAA9507944

• Gene Names: GPR132; G2A
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Synonyms: GPR132; Polyclonal Antibody; GPR132 Antibody; anti-GPR132 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: GPR132 Antibody detects endogenous levels of total GPR132 protein.
• Purity/Purification: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 371

• Applicable Applications for anti-GPR132 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500~1:1000; ELISA: 1:5000
• Target Modification: Unmodified/Total
• Immunogen: The antiserum was produced against synthesized peptide derived from human GPR132.
• Immunogen Range: 293-342
• Preparation and Storage: Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysates from COS7 cells, using GPR132 Antibody. The lane on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 524579300
• NCBI GeneID: 29933
• NCBI Accession #: NP_001265623.1
• NCBI GenBank Nucleotide #: NM_001278694.1
• UniProt Accession #: Q9UNW8; Q9BSU2; A8K7X7; B4E144
• Molecular Weight: 42 kDa
• NCBI Official Full Name: probable G-protein coupled receptor 132 isoform 1
• NCBI Official Synonym Full Names: G protein-coupled receptor 132
• NCBI Official Symbol: GPR132
• NCBI Official Synonym Symbols: G2A
• NCBI Protein Information: probable G-protein coupled receptor 132
• UniProt Protein Name: Probable G-protein coupled receptor 132
• Protein Family: Probable G-protein coupled receptor
• UniProt Gene Name: GPR132
• UniProt Synonym Gene Names: G2A

NCBI Description

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton-sensing activity.