Western Blot (WB)
(GPM6B Antibody (N-term) western blot analysis in ZR-75-1,CEM cell line lysates (35ug/lane).This demonstrates the GPM6B antibody detected the GPM6B protein (arrow).)
Rabbit GPM6B Polyclonal Antibody | anti-GPM6B antibody
GPM6B Antibody (N-term)
FC~~1:10~50
Western Blot (WB)
(GPM6B Antibody (N-term) western blot analysis in ZR-75-1,CEM cell line lysates (35ug/lane).This demonstrates the GPM6B antibody detected the GPM6B protein (arrow).)
Western Blot (WB)
(GPM6B Antibody (N-term) western blot analysis in ZR-75-1,CEM cell line lysates (35ug/lane).This demonstrates the GPM6B antibody detected the GPM6B protein (arrow).)
Flow Cytometry (FC/FACS)
(GPM6B Antibody (N-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(GPM6B Antibody (N-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
the proteolipid protein family. Proteolipid protein family members
are expressed in most brain regions and are thought to be involved
in cellular housekeeping functions, such as membrane trafficking
and cell-to-cell communication.
Sebastiani, P., et al. Am. J. Hematol. 83(3):189-195(2008)
Combes, P., et al. Neurogenetics 7(1):31-37(2006)
Henneke, M., et al. Am. J. Med. Genet. A 128A (2), 156-158 (2004) :
Werner, H., et al. Mol. Cell. Neurosci. 18(6):593-605(2001)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions, such as membrane trafficking and cell-to-cell communication. [provided by RefSeq, Apr 2009]
Uniprot Description
GPM6B: May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake. Belongs to the myelin proteolipid protein family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component: integral to membrane; plasma membrane; lipid raft
Biological Process: negative regulation of serotonin uptake; nervous system development; protein transport; ossification; regulation of actin cytoskeleton organization and biogenesis; regulation of focal adhesion formation; cell differentiation; positive regulation of bone mineralization
Research Articles on GPM6B
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Product Notes
The GPM6B gpm6b (Catalog #AAA9206791) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The GPM6B Antibody (N-term) reacts with Human (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's GPM6B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000 FC~~1:10~50. Researchers should empirically determine the suitability of the GPM6B gpm6b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPM6B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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