Rabbit anti-Human GPKOW Polyclonal Antibody | anti-GPKOW antibody

GPKOW, ID (GPKOW, GPATC5, GPATCH5, T54, G patch domain and KOW motifs-containing protein, G patch domain-containing protein 5, Protein MOS2 homolog, Protein T54) (PE)

Cat. Num. AAA6303578

• Gene Names: GPKOW; T54; Spp2; GPATC5; GPATCH5
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GPKOW; Polyclonal Antibody; ID (GPKOW; GPATC5; GPATCH5; T54; G patch domain and KOW motifs-containing protein; G patch domain-containing protein 5; Protein MOS2 homolog; Protein T54) (PE); Protein T54; anti-GPKOW antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-GPKOW antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: GPKOW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-338 amino acids from the Central region of human GPKOW.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(GPKOW Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the GPKOW antibody detected the GPKOW protein (arrow).)

Related Product Information for anti-GPKOW antibody

T54, also known as GPKOW (G patch domain and KOW motifs), GPATC5 or GPATCH5 (G patch domain-containing protein 5), is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.

Product Categories/Family for anti-GPKOW antibody

Antibodies; Proteins

References

Lamesch, P., et al. Genomics 89(3):307-315(2007). Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006). Zhang, Y., et al. Curr. Biol. 15(21):1936-1942(2005). Schindelhauer, D., et al. Genome Res. 6(11):1056-1069(1996).

NCBI and Uniprot Product Information

• NCBI GI #: 15811782
• NCBI GeneID: 27238
• NCBI Accession #: NP_056513.2
• NCBI GenBank Nucleotide #: NM_015698.5
• UniProt Accession #: Q92917; Q59EK5; Q9BQA8
• Molecular Weight: 52,229 Da
• NCBI Official Full Name: G patch domain and KOW motifs-containing protein
• NCBI Official Synonym Full Names: G-patch domain and KOW motifs
• NCBI Official Symbol: GPKOW
• NCBI Official Synonym Symbols: T54; Spp2; GPATC5; GPATCH5
• NCBI Protein Information: G patch domain and KOW motifs-containing protein
• UniProt Protein Name: G patch domain and KOW motifs-containing protein
• Protein Family: G patch domain and KOW motifs-containing protein
• UniProt Gene Name: GPKOW
• UniProt Synonym Gene Names: GPATC5; GPATCH5; T54
• UniProt Entry Name: GPKOW_HUMAN

NCBI Description

This gene encodes a putative RNA-binding protein containing G-patch and KOW (Kyprides, Ouzounis, Woese) domains. The encoded protein interacts directly with protein kinase A and protein kinase X and is also found associated with the spliceosome. [provided by RefSeq, Aug 2013]