Western Blot (WB)
(The anti-GPIP137 Pab is used in Western blot to detect GPIP137 in HL-60 cell lysate.)
Rabbit anti-Human GPIP137 Polyclonal Antibody | anti-CAPRIN1 antibody
GPIP137 Antibody (C-term)
Gene Names
CAPRIN1; M11S1; GPIAP1; RNG105; GPIP137; GRIP137; p137GPI
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GPIP137; Polyclonal Antibody; GPIP137 Antibody (C-term); Caprin-1; Cell cycle-associated protein 1; Cytoplasmic activation- and proliferation-associated protein 1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; p137GPI; Membrane component chromosome 11 surface marker 1; RNA granule protein 105; CAPRIN1; GPIAP1; M11S1; RNG105; anti-CAPRIN1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GPIP137 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 615-649 amino acids from the C-terminal region of human GPIP137.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
615-649
Sequence Length
694
Applicable Applications for anti-CAPRIN1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(The anti-GPIP137 Pab is used in Western blot to detect GPIP137 in HL-60 cell lysate.)
Western Blot (WB)
(The anti-GPIP137 Pab is used in Western blot to detect GPIP137 in HL-60 cell lysate.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Related Product Information for anti-CAPRIN1 antibody
GPIP137 may regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. It is expressed in the cytoplasm.
Product Categories/Family for anti-CAPRIN1 antibody
References
Gessler, M., et al., Genomics 32(1):169-170 (1996).
Ellis, J.A., et al., J. Biol. Chem. 270(35):20717-20723 (1995).
Ellis, J.A., et al., J. Biol. Chem. 270(35):20717-20723 (1995).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78366
NCBI Official Full Name
caprin-1 isoform 1
NCBI Official Synonym Full Names
cell cycle associated protein 1
NCBI Official Symbol
CAPRIN1
NCBI Official Synonym Symbols
M11S1; GPIAP1; RNG105; GPIP137; GRIP137; p137GPI
NCBI Protein Information
caprin-1
UniProt Protein Name
Caprin-1
Protein Family
UniProt Gene Name
CAPRIN1
UniProt Synonym Gene Names
GPIAP1; GPIP137; M11S1; RNG105; GPI-p137; p137GPI
UniProt Entry Name
CAPR1_HUMAN
Uniprot Description
CAPRIN1: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Belongs to the caprin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell surface; RNA-binding
Chromosomal Location of Human Ortholog: 11p13
Cellular Component: membrane; stress granule; integral to plasma membrane; dendrite; cytoplasm; cytosol
Molecular Function: RNA binding
Biological Process: negative regulation of translation; positive regulation of dendrite morphogenesis
Research Articles on CAPRIN1
Similar Products
Product Notes
The CAPRIN1 caprin1 (Catalog #AAA9214915) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 615-649. The GPIP137 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPIP137 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the CAPRIN1 caprin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPIP137, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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