Western Blot (WB)
(Western blot analysis of GPAM expression in mouse heart (A), mouse lung (B), rat brain (C) whole cell lysates.)
Rabbit anti-Human, Mouse GPAM Polyclonal Antibody | anti-GPAM antibody
Anti-GPAM Antibody
Western Blot (WB)
(Western blot analysis of GPAM expression in mouse heart (A), mouse lung (B), rat brain (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of GPAM expression in mouse heart (A), mouse lung (B), rat brain (C) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of GPAM staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of GPAM staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
GPAM: glycerol-3-phosphate acyltransferase is an integral multi-pass enzyme of the mitochondrial outer membrane. It performs the first step in de novo phospholipid biosynthesis. Member of the phospholipid and glycerol acyltransferase family
Protein type: Lipid Metabolism - glycerophospholipid; Transferase; Lipid Metabolism - glycerolipid; Mitochondrial; EC 2.3.1.15; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 10q25.2
Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrial outer membrane; plasma membrane
Molecular Function: glycerol-3-phosphate O-acyltransferase activity
Biological Process: acyl-CoA metabolic process; CDP-diacylglycerol biosynthetic process; cellular response to insulin stimulus; defense response to virus; fatty acid homeostasis; fatty acid metabolic process; phosphatidic acid biosynthetic process; phospholipid homeostasis; positive regulation of activated T cell proliferation; positive regulation of multicellular organism growth; regulation of cytokine secretion; response to activity; response to cadmium ion; response to fructose stimulus; response to glucose stimulus; response to nutrient levels; triacylglycerol biosynthetic process
Research Articles on GPAM
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Product Notes
The GPAM gpam (Catalog #AAA8245198) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GPAM Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GPAM can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1/500 - 1/2000; IHC: 1/50 - 1/200. Researchers should empirically determine the suitability of the GPAM gpam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPAM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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