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Rabbit Golgin A4 Polyclonal Antibody | anti-GOLGA4 antibody

Golgin A4 Antibody FITC-Conjugated

Gene Names
GOLGA4; GCP2; GOLG; p230; CRPF46; MU-RMS-40.18
Reactivity
Human, Monkey
Applications
ELISA, Immunoprecipitation, Western Blot
Synonyms
Golgin A4; Polyclonal Antibody; Golgin A4 Antibody FITC-Conjugated; 256 kDa golgin; 72.1 protein; GCP2; GOLG; GOLGA4; Golgin subfamily A member 4; golgin-240; Golgin-245; MU-RMS-40.18; p230; Protein 72.1; Trans-Golgi p230 antibody; anti-GOLGA4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Monkey
Clonality
Polyclonal
Form/Format
FITC-Conjugated
Concentration
0.55-0.75 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
2083
Applicable Applications for anti-GOLGA4 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 2025-2075 on human Golgin-245 protein.
Expression
Homodimer. Interacts with GTP bound ARL1. Interacts with MACF1.
Molecular Function
GTPase binding; Golgi to plasma membrane protein transport
Structure
Extended rod-like protein with coiled-coil domains. Ctonains 1 GRIP domain.
Subcellular Location
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-GOLGA4 antibody
FITC-Conjugated Golgin-245 Antibody
May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
262,328 Da
NCBI Official Full Name
golgin-245
NCBI Official Synonym Full Names
golgin A4
NCBI Official Symbol
GOLGA4
NCBI Official Synonym Symbols
GCP2; GOLG; p230; CRPF46; MU-RMS-40.18
NCBI Protein Information
golgin subfamily A member 4
UniProt Protein Name
Golgin subfamily A member 4
Protein Family
UniProt Gene Name
GOLGA4
UniProt Entry Name
GOGA4_HUMAN

NCBI Description

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]

Uniprot Description

GOLGA4: May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 3p22-p21.3

Cellular Component: cytoplasm; cytosol; Golgi apparatus; Golgi membrane; intracellular membrane-bound organelle; nucleoplasm; trans-Golgi network

Molecular Function: GTPase binding; protein binding

Biological Process: Golgi to plasma membrane protein transport; positive regulation of axon extension; protein targeting to Golgi; vesicle-mediated transport

Research Articles on GOLGA4

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Product Notes

The GOLGA4 golga4 (Catalog #AAA541744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Golgin A4 Antibody FITC-Conjugated reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's Golgin A4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Immunoprecipitation: 1:150 Western Blot: 1:500. Researchers should empirically determine the suitability of the GOLGA4 golga4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Golgin A4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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