Rabbit GNPAT Polyclonal Antibody | anti-GNPAT antibody
GNPAT Antibody
IHC: 1:50-1:200
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7129006(GNPAT Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7129006(GNPAT Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. [provided by RefSeq, Jul 2008]
Uniprot Description
GNPAT: Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2). RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation. Belongs to the GPAT/DAPAT family.
Protein type: EC 2.3.1.42; Lipid Metabolism - glycerophospholipid; Transferase
Chromosomal Location of Human Ortholog: 1q42
Cellular Component: peroxisomal membrane; peroxisomal matrix; membrane; mitochondrion; peroxisome
Molecular Function: glycerone-phosphate O-acyltransferase activity; palmitoyl-CoA hydrolase activity; receptor binding
Biological Process: response to starvation; response to drug; synaptogenesis; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; cerebellum morphogenesis; cellular lipid metabolic process; response to nutrient; ether lipid biosynthetic process; paranodal junction assembly
Disease: Rhizomelic Chondrodysplasia Punctata, Type 2
Research Articles on GNPAT
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Product Notes
The GNPAT gnpat (Catalog #AAA7129006) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GNPAT Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GNPAT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the GNPAT gnpat for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNPAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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