Rabbit GNAZ Polyclonal Antibody | anti-GNAZ antibody

GNAZ (Guanine nucleotide-binding protein G(z) subunit alpha, G(x) alpha chain) (AP)

Cat. Num. AAA6418785

• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: GNAZ; Polyclonal Antibody; GNAZ (Guanine nucleotide-binding protein G(z) subunit alpha; G(x) alpha chain) (AP); anti-GNAZ antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes GNAZ. Species Crossreactivity: human, mouse, rat
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-GNAZ antibody: Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: IHC: 1:50-1:100; WB: 1:500-1:2000; Applications are based on unconjugated antibody.
• Immunogen: Recombinant protein corresponding to human GNAZ.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using GNAZ antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using GNAZ antibody.)

Product Categories/Family for anti-GNAZ antibody

Antibodies; Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 121005
• NCBI GeneID: 2781
• UniProt Accession #: P19086; Q4QRJ6; B2R6C1
• Molecular Weight: 355
• NCBI Official Full Name: Guanine nucleotide-binding protein G(z) subunit alpha
• NCBI Official Synonym Full Names: guanine nucleotide binding protein (G protein), alpha z polypeptide
• NCBI Official Symbol: GNAZ
• NCBI Protein Information: guanine nucleotide-binding protein G(z) subunit alpha; guanine nucleotide-binding protein G(z) subunit alpha; gz-alpha; g(x) alpha chain; transducin alpha
• UniProt Protein Name: Guanine nucleotide-binding protein G(z) subunit alpha
• UniProt Gene Name: GNAZ
• UniProt Entry Name: GNAZ_HUMAN

NCBI Description

The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008]

Uniprot Description

G-alpha(z): Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Protein type: Nuclear envelope; Endoplasmic reticulum; G protein, heterotrimeric; G protein, heterotrimeric alpha G((i/o/t/z))

Chromosomal Location of Human Ortholog: 22q11.22

Cellular Component: endoplasmic reticulum; plasma membrane; heterotrimeric G-protein complex; nuclear envelope; cytosol

Molecular Function: GTPase activity; signal transducer activity; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; receptor signaling protein activity; metabotropic serotonin receptor binding

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; metabolic process; G-protein signaling, adenylate cyclase inhibiting pathway