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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreas tissue slide using MBS769768 (NESP55, GNAS Antibody) at dilution of 1:200)

Rabbit GNAS Polyclonal Antibody | anti-GNAS antibody

GNAS Rabbit Polyclonal

Gene Names
GNAS; SCG6; GNAS1; NESP55
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Immunohistochemistry, Western Blot
Purity
Purification: Immunogen affinity purified
Purity: > =95% as determined by SDS-PAGE
Synonyms
GNAS; Polyclonal Antibody; GNAS Rabbit Polyclonal; GNAS1; anti-GNAS antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purification: Immunogen affinity purified
Purity: > =95% as determined by SDS-PAGE
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Applicable Applications for anti-GNAS antibody
ELISA (EIA), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Immunogen
GNAS complex locus
Preparation and Storage
-20 degree C for 12 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreas tissue slide using MBS769768 (NESP55, GNAS Antibody) at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreas tissue slide using MBS769768 (NESP55, GNAS Antibody) at dilution of 1:200)

Immunoprecipitation (IP)

(IP Result of anti-GNAS (IP: MBS769768, 4ug; Detection: MBS769768 1:300) with mouse liver tissue lysate 4000ug.)

Immunoprecipitation (IP) (IP Result of anti-GNAS (IP: MBS769768, 4ug; Detection: MBS769768 1:300) with mouse liver tissue lysate 4000ug.)

Western Blot (WB)

(Mouse liver tissue were subjected to SDS-PAGE followed by western blot with MBS769768 (NESP55, GNAS Antibody) at dilution of 1:1000)

Western Blot (WB) (Mouse liver tissue were subjected to SDS-PAGE followed by western blot with MBS769768 (NESP55, GNAS Antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed MW: 46 kDa
NCBI Official Full Name
GNAS complex locus isoform GNASL
NCBI Official Symbol
GNAS
NCBI Official Synonym Symbols
SCG6; GNAS1; NESP55
NCBI Protein Information
GNAS complex locus; SCG6 (secretogranin VI)
UniProt Protein Name
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Protein Family
UniProt Gene Name
GNAS
UniProt Synonym Gene Names
GNAS1
UniProt Entry Name
GNAS2_BOVIN

Uniprot Description

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:2022671, PubMed:9395396, PubMed:11087399, PubMed:15591060, PubMed:16766715, PubMed:19243146). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2 ().

Research Articles on GNAS

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Product Notes

The GNAS gnas (Catalog #AAA769768) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GNAS Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GNAS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blot (WB). WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200. Researchers should empirically determine the suitability of the GNAS gnas for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNAS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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