Rabbit anti-Human GNA14 Polyclonal Antibody | anti-GNA14 antibody

GNA14 Antibody

Cat. Num. AAA9408052

• Reactivity: Human
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: GNA14; Polyclonal Antibody; GNA14 Antibody; Guanine nucleotide-binding protein alpha-14 subunit; G-protein alpha subunit 14; anti-GNA14 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total GNA14 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 355

• Applicable Applications for anti-GNA14 antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:500~1:3000
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from N-terminal of human GNA14.
• Target Name: GNA14
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from HuvEc cells, using GNA14 antibody.)

Related Product Information for anti-GNA14 antibody

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.Rubio J.P., Genomics 57:84-93(1999).Puhl H.L. III, Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.The MGC Project Team, Genome Res. 14:2121-2127(2004).

Product Categories/Family for anti-GNA14 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 4758444
• NCBI GeneID: 9630
• NCBI Accession #: NP_004288.1
• NCBI GenBank Nucleotide #: NM_004297.3
• UniProt Accession #: O95837; B1ALW3
• Molecular Weight: 41,571 Da
• NCBI Official Full Name: guanine nucleotide-binding protein subunit alpha-14
• NCBI Official Synonym Full Names: guanine nucleotide binding protein (G protein), alpha 14
• NCBI Official Symbol: GNA14
• NCBI Protein Information: guanine nucleotide-binding protein subunit alpha-14
• UniProt Protein Name: Guanine nucleotide-binding protein subunit alpha-14
• Protein Family: Guanine nucleotide-binding protein
• UniProt Gene Name: GNA14
• UniProt Synonym Gene Names: G alpha-14; G-protein subunit alpha-14
• UniProt Entry Name: GNA14_HUMAN

NCBI Description

This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009]

Uniprot Description

G-alpha 14: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Belongs to the G-alpha family. G(q) subfamily.

Protein type: G protein; G protein, heterotrimeric alpha G(q); G protein, heterotrimeric

Chromosomal Location of Human Ortholog: 9q21

Cellular Component: plasma membrane; heterotrimeric G-protein complex

Molecular Function: GTPase activity; signal transducer activity; GTP binding; G-protein-coupled receptor binding; metal ion binding; G-protein beta/gamma-subunit binding

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; platelet activation; metabolic process; dopamine receptor, phospholipase C activating pathway; signal transduction; blood coagulation