Western Blot (WB)
(Western blot analysis of GNA13 expression in BT474 (A), THP1 (B), mouse lung (C), mouse spleen (D) whole cell lysates.)
Rabbit GNA13 Polyclonal Antibody | anti-GNA13 antibody
Anti-GNA13 Antibody
Western Blot (WB)
(Western blot analysis of GNA13 expression in BT474 (A), THP1 (B), mouse lung (C), mouse spleen (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of GNA13 expression in BT474 (A), THP1 (B), mouse lung (C), mouse spleen (D) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of GNA13 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of GNA13 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
Uniprot Description
G-alpha 13: a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. Activates Rho. Protein kinase A blocks Rho activation by phosphorylation of G-alpha(13). Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Regulates cytoplasmic as well as nuclear signaling events such as activation of the Jun N-terminal kinase signaling module, Na+/H+ exchangers, focal adhesion assemblies, and transcriptional activation of specific primary response genes.
Protein type: G protein; G protein, heterotrimeric; G protein, heterotrimeric alpha G(12)
Chromosomal Location of Human Ortholog: 17q24.3
Cellular Component: brush border membrane; cytoplasm; focal adhesion; heterotrimeric G-protein complex; membrane; plasma membrane
Molecular Function: D5 dopamine receptor binding; G-protein beta/gamma-subunit binding; GTPase activity; protein binding; signal transducer activity; type 1 angiotensin receptor binding
Biological Process: cell motility; G-protein signaling, adenylate cyclase activating pathway; phospholipase D activation; platelet activation; Rho protein signal transduction; signal transduction
Research Articles on GNA13
Similar Products
Product Notes
The GNA13 gna13 (Catalog #AAA8247398) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GNA13 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GNA13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1/500 - 1/2000; IHC: 1/50 - 1/200. Researchers should empirically determine the suitability of the GNA13 gna13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNA13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
