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Western Blot (WB) (Western blot analysis of anti-GNA12 Antibody (S67) in A2058 cell line lysates (35ug/lane). GNA12(arrow) was detected using the purified Pab.)

Rabbit GNA12 Polyclonal Antibody | anti-GNA12 antibody

GNA12 Antibody (S67)

Gene Names
GNA12; RMP; gep; NNX3
Reactivity
Human (Predicted Reactivity: Mouse, Rat, Drosophila)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GNA12; Polyclonal Antibody; GNA12 Antibody (S67); Guanine nucleotide-binding protein subunit alpha-12; G alpha-12; G-protein subunit alpha-12; anti-GNA12 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat, Drosophila)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GNA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from human GNA12.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
46-75
Sequence Length
288
Applicable Applications for anti-GNA12 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of anti-GNA12 Antibody (S67) in A2058 cell line lysates (35ug/lane). GNA12(arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of anti-GNA12 Antibody (S67) in A2058 cell line lysates (35ug/lane). GNA12(arrow) was detected using the purified Pab.)
Related Product Information for anti-GNA12 antibody
Guanine nucleotide-binding proteins (G proteins) are modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 subunits; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Product Categories/Family for anti-GNA12 antibody
References
Krakstad, B.F., et al., Proc. Natl. Acad. Sci. U.S.A. 101(28):10314-10319 (2004).
Hillier, L.W., et al., Nature 424(6945):157-164 (2003).
Scherer, S.W., et al., Science 300(5620):767-772 (2003).
Suzuki, N., et al., Proc. Natl. Acad. Sci. U.S.A. 100(2):733-738 (2003).
Yamaguchi, Y., et al., J. Biol. Chem. 278(17):14936-14939 (2003).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44279
NCBI Official Full Name
guanine nucleotide-binding protein subunit alpha-12 isoform 1
NCBI Official Synonym Full Names
guanine nucleotide binding protein (G protein) alpha 12
NCBI Official Symbol
GNA12
NCBI Official Synonym Symbols
RMP; gep; NNX3
NCBI Protein Information
guanine nucleotide-binding protein subunit alpha-12
UniProt Protein Name
Guanine nucleotide-binding protein subunit alpha-12
UniProt Gene Name
GNA12
UniProt Synonym Gene Names
G alpha-12; G-protein subunit alpha-12
UniProt Entry Name
GNA12_HUMAN

Uniprot Description

G-alpha 12: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Belongs to the G-alpha family. G(12) subfamily.

Protein type: G protein, heterotrimeric alpha G(12); G protein, heterotrimeric; G protein

Chromosomal Location of Human Ortholog: 7p22.2

Cellular Component: focal adhesion; brush border membrane; plasma membrane; heterotrimeric G-protein complex

Molecular Function: GTPase activity; protein binding; signal transducer activity; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; D5 dopamine receptor binding

Biological Process: response to drug; platelet activation; in utero embryonic development; metabolic process; regulation of proteasomal ubiquitin-dependent protein catabolic process; Rho protein signal transduction; regulation of TOR signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; regulation of cell shape; embryonic digit morphogenesis; cell differentiation; blood coagulation

Research Articles on GNA12

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Product Notes

The GNA12 gna12 (Catalog #AAA9212073) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 46-75. The GNA12 Antibody (S67) reacts with Human (Predicted Reactivity: Mouse, Rat, Drosophila) and may cross-react with other species as described in the data sheet. AAA Biotech's GNA12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GNA12 gna12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNA12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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