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Western Blot (WB) (All lanes : Anti-GMPPB Antibody (N-Term) at 1:2000 dilutionLane 1: human pancreas lysateLane 2: mouse pancreas lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit GMPPB Polyclonal Antibody | anti-GMPPB antibody

GMPPB Antibody (N-Term)

Gene Names
GMPPB; MDDGA14; MDDGB14; MDDGC14
Reactivity
Human, Mouse; Predicted Reactivity: Mouse, Pig
Applications
Western Blot, ELISA
Synonyms
GMPPB; Polyclonal Antibody; GMPPB Antibody (N-Term); Mannose-1-phosphate guanyltransferase beta; 2.7.7.13; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; anti-GMPPB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse; Predicted Reactivity: Mouse, Pig
Clonality
Polyclonal
Isotype
Ig
Specificity
This GMPPB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-74 amino acids from human GMPPB.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
387
Applicable Applications for anti-GMPPB antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB:~~1:2000
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Cellular Location
Cytoplasm.
Antigen Type
Synthesized Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-GMPPB Antibody (N-Term) at 1:2000 dilutionLane 1: human pancreas lysateLane 2: mouse pancreas lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-GMPPB Antibody (N-Term) at 1:2000 dilutionLane 1: human pancreas lysateLane 2: mouse pancreas lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Product Categories/Family for anti-GMPPB antibody
References
Matthijs G.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45 (2004). Muzny D.M.,et al.Nature 440:1194-1198 (2006). Burkard T.R.,et al.BMC Syst. Biol. 5:17-17 (2011). Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454 (2012).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39834 Da
NCBI Official Full Name
mannose-1-phosphate guanyltransferase beta isoform 1
NCBI Official Synonym Full Names
GDP-mannose pyrophosphorylase B
NCBI Official Symbol
GMPPB
NCBI Official Synonym Symbols
MDDGA14; MDDGB14; MDDGC14
NCBI Protein Information
mannose-1-phosphate guanyltransferase beta
UniProt Protein Name
Mannose-1-phosphate guanyltransferase beta
UniProt Gene Name
GMPPB
UniProt Entry Name
GMPPB_HUMAN

NCBI Description

This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009]

Uniprot Description

GMPPB: This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009]

Protein type: Motility/polarity/chemotaxis; Transferase; EC 2.7.7.13; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - amino sugar and nucleotide sugar

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: cytoplasm; mitochondrion

Molecular Function: GTP binding; mannose-1-phosphate guanylyltransferase activity; protein binding

Biological Process: GDP-mannose biosynthetic process

Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 14; Muscular Dystrophy-dystroglycanopathy (congenital With Mental Retardation), Type B, 14; Muscular Dystrophy-dystroglycanopathy (limb-girdle), Type C, 14

Research Articles on GMPPB

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Product Notes

The GMPPB gmppb (Catalog #AAA9217197) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GMPPB Antibody (N-Term) reacts with Human, Mouse; Predicted Reactivity: Mouse, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's GMPPB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB:~~1:2000. Researchers should empirically determine the suitability of the GMPPB gmppb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GMPPB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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