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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)

Rabbit anti-Human GM-CSF Polyclonal Antibody | anti-GM-CSF antibody

GM-CSF Polyclonal Antibody

Gene Names
CSF2; GMCSF
Reactivity
Human
Applications
Immunohistochemistry
Purity
Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Synonyms
GM-CSF; Polyclonal Antibody; GM-CSF Polyclonal Antibody; Granulocyte-macrophage colony-stimulating factor (GM-CSF) (Colony-stimulating factor) (CSF) (Molgramostin) (Sargramostim); anti-GM-CSF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous GM-CSF
Purity/Purification
Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Form/Format
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Concentration
1 mg/ml (varies by lot)
Applicable Applications for anti-GM-CSF antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-300
Immunogen
Synthetic peptide from human protein at AA range: 100-144
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)
Product Categories/Family for anti-GM-CSF antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,295 Da
NCBI Official Full Name
granulocyte-macrophage colony-stimulating factor
NCBI Official Synonym Full Names
colony stimulating factor 2
NCBI Official Symbol
CSF2
NCBI Official Synonym Symbols
GMCSF
NCBI Protein Information
granulocyte-macrophage colony-stimulating factor
UniProt Protein Name
Granulocyte-macrophage colony-stimulating factor
UniProt Gene Name
CSF2
UniProt Synonym Gene Names
GMCSF; GM-CSF; CSF

NCBI Description

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]

Uniprot Description

GMCSF: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular region; extracellular space; intracellular membrane-bound organelle

Molecular Function: cytokine activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity

Biological Process: MAPKKK cascade; myeloid dendritic cell differentiation; negative regulation of cytolysis; positive regulation of DNA replication; positive regulation of interleukin-23 production; positive regulation of tyrosine phosphorylation of STAT protein

Research Articles on GM-CSF

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Product Notes

The GM-CSF csf2 (Catalog #AAA9419869) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GM-CSF Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GM-CSF can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-300. Researchers should empirically determine the suitability of the GM-CSF csf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GM-CSF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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