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Rabbit anti-Human GLUT12 Polyclonal Antibody | anti-GLUT12 antibody

GLUT12 antibody

Gene Names
SLC2A12; GLUT8; GLUT12
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
GLUT12 antibody was purified by affinity chromatography.
Synonyms
GLUT12; Polyclonal Antibody; GLUT12 antibody; Polyclonal GLUT12; Anti-GLUT12; GLUT -12; GLUT-12; GLUT 12; Glucose Transporter 12; anti-GLUT12 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
GLUT12 antibody was purified by affinity chromatography.
Form/Format
Lyophilized from Tris, pH 7.5, with 0.02% BSA, and 0.05% NaN3. Reconstitute in PBS to a concentration of 1 mg/ml.
Sequence Length
617
Applicable Applications for anti-GLUT12 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
ELISA: 0.5-1 ug/ml
IHC: 2-10 ug/ml
WB: 1-10 ug/ml
Biological Significance
Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Glut-12 (human 617 aa,, monkey 621 aa;~ 50 kDa; ~30% homology with Glut-4 and 40% with Glut-10) is expressed in skeletal muscle, adipose tissue, and small intestine.
Immunogen
GLUT12 antibody was raised in rabbit using a 15 amino acid peptide from human GT122 as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-GLUT12 antibody
Affinity purified Rabbit polyclonal GLUT12 antibody
Product Categories/Family for anti-GLUT12 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
66,966 Da
NCBI Official Full Name
glucose transporter protein 12
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 12
NCBI Official Symbol
SLC2A12
NCBI Official Synonym Symbols
GLUT8; GLUT12
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 12
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 12
UniProt Gene Name
SLC2A12
UniProt Synonym Gene Names
GLUT12; GLUT8; GLUT-12
UniProt Entry Name
GTR12_HUMAN

NCBI Description

SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]

Uniprot Description

GLUT12: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Expressed in the heart, skeletal muscle, brown adipose tissue, and prostate.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: perinuclear region of cytoplasm; integral to membrane; plasma membrane; endomembrane system

Molecular Function: substrate-specific transmembrane transporter activity

Biological Process: glucose transport; transmembrane transport

Research Articles on GLUT12

Similar Products

Product Notes

The GLUT12 slc2a12 (Catalog #AAA534696) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GLUT12 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GLUT12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). ELISA: 0.5-1 ug/ml IHC: 2-10 ug/ml WB: 1-10 ug/ml. Researchers should empirically determine the suitability of the GLUT12 slc2a12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLUT12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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