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Western Blot (WB)

Rabbit Glucose-6-Phosphate Polyclonal Antibody | anti-G6pc2 antibody

Glucose-6-Phosphate, catalytic subunit Antibody Affinity Purified

Reactivity
Human, Monkey, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Synonyms
Glucose-6-Phosphate; Polyclonal Antibody; catalytic subunit Antibody Affinity Purified; AW107337; G-6-Pase; g6pc; G6PT; Glucose-6-phosphatase alpha; GSD1; GSD1a; MGC163350; MGC93613; RP23-281C18.19 antibody; anti-G6pc2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.55-0.65 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
154
Applicable Applications for anti-G6pc2 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 80-130 on G6PC2 protein, and common in larger variant of glucose 6 phosphatase.
Expression
Specifically expressed in pancreatic islet cells, in particular those of beta-cell origin. Not detected in testis, kidney, muscle, liver, lung, spleen, brain, pituitary, gastric fundus or heart.
Molecular Function
Gluconeogenesis
Structure
Belongs to the glucose-6-phosphatase family.
Subcellular Location
Endoplasmic Reticulum Membrane; Multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-G6pc2 antibody
Affinity Purified Glucose-6-phosphoate catalytic 2 Antibody
May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis.
Product Categories/Family for anti-G6pc2 antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
17,894 Da
UniProt Protein Name
Glucose-6-phosphatase 2
Protein Family
UniProt Gene Name
G6pc2
UniProt Synonym Gene Names
Igrp; G-6-Pase 2; G6Pase 2
UniProt Entry Name
G6PC2_MOUSE

Uniprot Description

G6PC2: May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis. Belongs to the glucose-6-phosphatase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - starch and sucrose; Endoplasmic reticulum; Membrane protein, multi-pass; Transporter; Carbohydrate Metabolism - galactose; Membrane protein, integral; Phosphatase (non-protein); Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 3.1.3.9; Transporter, SLC family

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to membrane; membrane

Molecular Function: glucose-6-phosphatase activity; hydrolase activity

Biological Process: dephosphorylation; gluconeogenesis; glucose 6-phosphate metabolic process; glucose homeostasis; regulation of insulin secretion

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Product Notes

The Glucose-6-Phosphate g6pc2 (Catalog #AAA540025) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glucose-6-Phosphate, catalytic subunit Antibody Affinity Purified reacts with Human, Monkey, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Glucose-6-Phosphate can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the Glucose-6-Phosphate g6pc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glucose-6-Phosphate, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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