Western Blot (WB)
(Western blot analysis of Glucagon Receptor expression in PC12 (A); Jurkat (B) whole cell lysates.)
Rabbit Glucagon Receptor Polyclonal Antibody | anti-GL-R antibody
Glucagon Receptor Antibody
IHC: 1:100-1:200
Western Blot (WB)
(Western blot analysis of Glucagon Receptor expression in PC12 (A); Jurkat (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Glucagon Receptor expression in PC12 (A); Jurkat (B) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]
Uniprot Description
GCGR: This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family.
Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17q25
Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane; endosome
Molecular Function: peptide hormone binding; guanyl-nucleotide exchange factor activity; glucagon receptor activity
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; response to starvation; generation of precursor metabolites and energy; exocytosis; hormone-mediated signaling; regulation of blood pressure; energy reserve metabolic process; glucose homeostasis; G-protein signaling, adenylate cyclase activating pathway; response to nutrient; positive regulation of GTPase activity
Disease: Diabetes Mellitus, Noninsulin-dependent
Research Articles on GL-R
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Product Notes
The GL-R gcgr (Catalog #AAA5314404) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Glucagon Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:100-1:200. Researchers should empirically determine the suitability of the GL-R gcgr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glucagon Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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