Western Blot (WB)
(Western Blot (WB) analysis of GIMAP4 polyclonal antibody at 1:500 dilutionLane1:CT26 whole cell lysate (40ug) Lane2:HCT116 whole cell lysate (40ug) Lane3:A2780 whole cell lysate (40ug) Lane4:The Spleen tissue lysate of Mouse (40ug) Lane5:The Spleen tissue lysate of Rat (40ug))
Rabbit GIMAP4 Polyclonal Antibody | anti-GIMAP4 antibody
GIMAP4 Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
GIMAP4; Polyclonal Antibody; GIMAP4 Polyclonal Antibody; GTPase IMAP family member 4; Immunity-associated nucleotide 1 protein; IAN-1; hIAN1; Immunity-associated protein 4; IMAP4; IAN1; MSTP062; anti-GIMAP4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
GIMAP4 polyclonal antibody detects endogenous levels of GIMAP4 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
329
Applicable Applications for anti-GIMAP4 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding Human GIMAP4.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of GIMAP4 polyclonal antibody at 1:500 dilutionLane1:CT26 whole cell lysate (40ug) Lane2:HCT116 whole cell lysate (40ug) Lane3:A2780 whole cell lysate (40ug) Lane4:The Spleen tissue lysate of Mouse (40ug) Lane5:The Spleen tissue lysate of Rat (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of GIMAP4 polyclonal antibody at 1:500 dilutionLane1:CT26 whole cell lysate (40ug) Lane2:HCT116 whole cell lysate (40ug) Lane3:A2780 whole cell lysate (40ug) Lane4:The Spleen tissue lysate of Mouse (40ug) Lane5:The Spleen tissue lysate of Rat (40ug))
Related Product Information for anti-GIMAP4 antibody
The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP4 (GTPase IMAP family member 4), also known as IMAP4 (immunity-associated protein 4) and IAN1 (immunityassociated nucleotide 1 protein), is a 329 amino acid protein that contains 5 motifs that are conserved in GTP-binding proteins and a C-terminal coiledcoiled region that may be responsible for protein-protein interactions. GIMAP4 exhibits intrinsic GTPase activity that is highly dependent on magnesium concentration to bind GDP. Showing differential regulation during T-helper cell differentiation, GIMAP4 appears to regulate the apoptosis of T cells. GIMAP4 is specifically expressed in resting T and B lymphocytes and its protein expression is appreciably decreased upon T or B lymphocyte activation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 37kDa
NCBI Official Full Name
GTPase IMAP family member 4 isoform 1
UniProt Protein Name
GTPase IMAP family member 4
Protein Family
UniProt Gene Name
GIMAP4
UniProt Synonym Gene Names
IAN1; IMAP4; IAN-1; hIAN1
UniProt Entry Name
GIMA4_HUMAN
Uniprot Description
GIMAP4: May play a role in regulating lymphocyte apoptosis. Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium. Belongs to the IAN GTP-binding protein family.
Protein type: Hydrolase
Chromosomal Location of Human Ortholog: 7q36.1
Cellular Component: cytosol
Molecular Function: GTP binding
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Product Notes
The GIMAP4 gimap4 (Catalog #AAA3007577) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GIMAP4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GIMAP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the GIMAP4 gimap4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GIMAP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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