Testing Data
(Tissue/cell: HUVEC cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GIMAP2) Polyclonal Antibody, Unconjugated at 1:150 overnight at 4°C.)
Rabbit anti-Human GIMAP2 Polyclonal Antibody | anti-GIMAP2 antibody
GIMAP2 Polyclonal Antibody
Gene Names
GIMAP2; IMAP2; HIMAP2
Reactivity
Human
Applications
Immunocytochemistry
Purity
affinity purified by Protein A
Synonyms
GIMAP2; Polyclonal Antibody; GIMAP2 Polyclonal Antibody; GTPase; IMAP family member 2; HIMAP2; IMAP2; Immunity associated protein 2; GIMA2_HUMAN; anti-GIMAP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
GIMAP2 Polyclonal Antibody detects endogenous levels of GIMAP2 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-GIMAP2 antibody
Immunocytochemistry (ICC)
Application Notes
ICC: 1:100-500
Immunogen
KLH conjugated synthetic peptide derived from human GIMAP2:21-120/337
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Testing Data
(Tissue/cell: HUVEC cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GIMAP2) Polyclonal Antibody, Unconjugated at 1:150 overnight at 4°C.)
Testing Data
(Tissue/cell: HUVEC cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GIMAP2) Polyclonal Antibody, Unconjugated at 1:150 overnight at 4°C.)
Related Product Information for anti-GIMAP2 antibody
The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP2 (GTPase IMAP family member 2), also known as IMAP2 (immunity-associated protein 2) or HIMAP2, is a 337 amino acid multi-pass membrane protein that is encoded by a gene located on human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,017 Da
NCBI Official Full Name
GTPase IMAP family member 2
NCBI Official Synonym Full Names
GTPase, IMAP family member 2
NCBI Official Symbol
GIMAP2
NCBI Official Synonym Symbols
IMAP2; HIMAP2
NCBI Protein Information
GTPase IMAP family member 2; immunity associated protein 2; immunity-associated protein 2
UniProt Protein Name
GTPase IMAP family member 2
Protein Family
UniProt Gene Name
GIMAP2
UniProt Synonym Gene Names
IMAP2; hIMAP2
UniProt Entry Name
GIMA2_HUMAN
NCBI Description
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Uniprot Description
GIMAP2: a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Protein type: Membrane protein, integral; Hydrolase; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 7q36.1
Cellular Component: cytoplasm; integral to membrane; lipid particle
Molecular Function: GTP binding
Research Articles on GIMAP2
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Product Notes
The GIMAP2 gimap2 (Catalog #AAA3005558) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GIMAP2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GIMAP2 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC). ICC: 1:100-500. Researchers should empirically determine the suitability of the GIMAP2 gimap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GIMAP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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