WB: 1:200-1:1000
IHC: 1:100-1:500
NCBI and Uniprot Product Information
NCBI Description
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]
Uniprot Description
GGT6: Cleaves glutathione conjugates. Belongs to the gamma-glutamyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Other Amino Acids Metabolism - taurine and hypotaurine; Other Amino Acids Metabolism - cyanoamino acid; Lipid Metabolism - arachidonic acid; EC 2.3.2.2; Other Amino Acids Metabolism - selenoamino acid; Transferase; Other Amino Acids Metabolism - glutathione; EC 3.4.19.13
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: anchored to external side of plasma membrane; integral to membrane
Molecular Function: gamma-glutamyltransferase activity
Biological Process: leukotriene biosynthetic process; glutathione metabolic process; glutathione biosynthetic process; proteolysis
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Product Notes
The GGT6 ggt6 (Catalog #AAA9409957) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GGT6 Antibody reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GGT6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20000-1:80000 WB: 1:200-1:1000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the GGT6 ggt6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GGT6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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