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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MBS7127267(GFRA3 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit GFRA3 Polyclonal Antibody | anti-GFRA3 antibody

GFRA3 Antibody

Gene Names
GFRA3; GDNFR3
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
GFRA3; Polyclonal Antibody; GFRA3 Antibody; GDNF family receptor alpha 3; anti-GFRA3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-GFRA3 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-1:10000
IHC: 1:50-1:150
Immunogen
Synthetic peptide of human GFRA3
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MBS7127267(GFRA3 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MBS7127267(GFRA3 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200))
Product Categories/Family for anti-GFRA3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
400
NCBI Official Full Name
GDNF family receptor alpha-3
NCBI Official Synonym Full Names
GDNF family receptor alpha 3
NCBI Official Symbol
GFRA3
NCBI Official Synonym Symbols
GDNFR3
NCBI Protein Information
GDNF family receptor alpha-3; GFR-alpha-3; GDNFR-alpha-3; GPI-linked receptor; GDNF receptor alpha-3; glial cell line-derived neurotrophic factor receptor alpha-3
UniProt Protein Name
GDNF family receptor alpha-3
Protein Family
UniProt Gene Name
GFRA3
UniProt Synonym Gene Names
GDNF receptor alpha-3; GDNFR-alpha-3; GFR-alpha-3
UniProt Entry Name
GFRA3_HUMAN

NCBI Description

The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. [provided by RefSeq, Jul 2008]

Uniprot Description

GFRA3: Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase. Belongs to the GDNFR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 5q31.1-q31.3

Cellular Component: extrinsic to membrane; intracellular membrane-bound organelle; cytoplasm; plasma membrane; external side of plasma membrane

Molecular Function: axon guidance receptor activity; receptor binding

Biological Process: axon guidance; nervous system development; sympathetic nervous system development; neuron migration; signal transduction; peripheral nervous system development

Research Articles on GFRA3

Similar Products

Product Notes

The GFRA3 gfra3 (Catalog #AAA7127267) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GFRA3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GFRA3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:1000-1:10000 IHC: 1:50-1:150. Researchers should empirically determine the suitability of the GFRA3 gfra3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GFRA3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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