Rabbit anti-Human GDPD2 Polyclonal Antibody | anti-GDPD2 antibody

GDPD2, ID (GDPD2, GDE3, OBDPF, Glycerophosphoinositol inositolphosphodiesterase GDPD2, Glycerophosphodiester phosphodiesterase 3, Glycerophosphodiester phosphodiesterase domain-containing protein 2, Osteoblast differentiation promoting factor) (FITC)

Cat. Num. AAA6301877

• Gene Names: GDPD2; GDE3; OBDPF
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GDPD2; Polyclonal Antibody; ID (GDPD2; GDE3; OBDPF; Glycerophosphoinositol inositolphosphodiesterase GDPD2; Glycerophosphodiester phosphodiesterase 3; Glycerophosphodiester phosphodiesterase domain-containing protein 2; Osteoblast differentiation promoting factor) (FITC); Osteoblast differentiation promoting factor; anti-GDPD2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
• Sequence Length: 539

• Applicable Applications for anti-GDPD2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: GDPD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-334 amino acids from the Central region of human GDPD2.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(GDPD2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the GDPD2 Antibody detected the GDPD2 protein (arrow).)

Related Product Information for anti-GDPD2 antibody

This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants.

Product Categories/Family for anti-GDPD2 antibody

Antibodies; Enzymes; Phosphodiesterase

References

Corda, D., et al. J. Biol. Chem. 284(37):24848-24856(2009). Yanaka, N., et al. J. Biol. Chem. 278(44):43595-43602(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 21361649
• NCBI GeneID: 54857
• NCBI Accession #: NP_060181.2
• NCBI GenBank Nucleotide #: NP_060181.2
• UniProt Accession #: Q9HCC8
• NCBI Official Full Name: glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 2
• NCBI Official Synonym Full Names: glycerophosphodiester phosphodiesterase domain containing 2
• NCBI Official Symbol: GDPD2
• NCBI Official Synonym Symbols: GDE3; OBDPF
• NCBI Protein Information: glycerophosphoinositol inositolphosphodiesterase GDPD2
• UniProt Protein Name: Glycerophosphoinositol inositolphosphodiesterase GDPD2
• Protein Family: Glycerophosphodiester phosphodiesterase
• UniProt Gene Name: GDPD2
• UniProt Synonym Gene Names: GDE3; OBDPF

NCBI Description

This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

Uniprot Description

GDPD2: Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton. Belongs to the glycerophosphoryl diester phosphodiesterase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.43; Membrane protein, integral; Membrane protein, multi-pass; Phosphodiesterase

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: actin filament; cytoplasm; integral component of membrane; lamellipodium; plasma membrane

Molecular Function: glycerophosphodiester phosphodiesterase activity; glycerophosphoinositol inositolphosphodiesterase activity; metal ion binding

Biological Process: lipid metabolic process; positive regulation of osteoblast differentiation