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Rabbit anti-Human GDP-L-fucose synthase Polyclonal Antibody | anti-TSTA3 antibody
Rabbit anti-human GDP-L-fucose synthase polyclonal Antibody, HRP conjugated
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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NCBI and Uniprot Product Information
NCBI Description
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008]
Uniprot Description
TSTA3: Two step NADP-dependent conversion of GDP-4-dehydro-6- deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the fucose synthase family.
Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Oxidoreductase; EC 1.1.1.271; Carbohydrate Metabolism - fructose and mannose
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: cytoplasm; cytosol
Molecular Function: coenzyme binding; electron carrier activity; GDP-4-dehydro-D-rhamnose reductase activity; GDP-L-fucose synthase activity; isomerase activity
Biological Process: 'de novo' GDP-L-fucose biosynthetic process; cellular protein metabolic process; cytolysis; dolichol-linked oligosaccharide biosynthetic process; GDP-mannose metabolic process; leukocyte adhesion; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine
Research Articles on TSTA3
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Product Notes
The TSTA3 tsta3 (Catalog #AAA719903) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human GDP-L-fucose synthase polyclonal Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GDP-L-fucose synthase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the TSTA3 tsta3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDP-L-fucose synthase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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