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Western Blot (WB)

Rabbit anti-Human GDF7 Polyclonal Antibody | anti-GDF7 antibody

Anti-GDF7 Antibody

Gene Names
GDF7; BMP12
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purification. The antibody was purified by affinity chromatography
Synonyms
GDF7; Polyclonal Antibody; Anti-GDF7 Antibody; Growth/differentiation factor 7; GDF-7; anti-GDF7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Polyclonal antibody to detect endogenous levels of GDF7 in human samples
Purity/Purification
Affinity purification. The antibody was purified by affinity chromatography
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH7.3; 30% glycerol and 0.01% sodium azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-GDF7 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:100-1:200
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GDF7
Positive Control
WB: HeLa cell lysate
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-GDF7 antibody
May play an active role in the motor area of the primate neocortex.
Product Categories/Family for anti-GDF7 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,950 Da
NCBI Official Full Name
growth/differentiation factor 7 preproprotein
NCBI Official Synonym Full Names
growth differentiation factor 7
NCBI Official Symbol
GDF7
NCBI Official Synonym Symbols
BMP12
NCBI Protein Information
growth/differentiation factor 7; GDF-7
UniProt Protein Name
Growth/differentiation factor 7
UniProt Gene Name
GDF7
UniProt Synonym Gene Names
GDF-7
UniProt Entry Name
GDF7_HUMAN

NCBI Description

This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq, Jul 2008]

Uniprot Description

GDF7: May play an active role in the motor area of the primate neocortex. Belongs to the TGF-beta family.

Protein type: Cytokine; Secreted, signal peptide; Cell development/differentiation; Secreted

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: extracellular space

Molecular Function: protein binding; protein homodimerization activity; growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: axon guidance; cell fate commitment; positive regulation of transcription, DNA-dependent; activin receptor signaling pathway; roof plate formation; forebrain morphogenesis; BMP signaling pathway; regulation of apoptosis; epithelial cell differentiation; branching morphogenesis of a tube; regulation of MAPKKK cascade; midbrain development; spinal cord association neuron differentiation; gland morphogenesis; positive regulation of neuron differentiation; cell development; reproductive structure development; growth

Research Articles on GDF7

Similar Products

Product Notes

The GDF7 gdf7 (Catalog #AAA847487) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GDF7 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GDF7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:100-1:200. Researchers should empirically determine the suitability of the GDF7 gdf7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDF7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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