Western Blot (WB)
(Western BlotPositive WB detected in:Mouse heart tissue,Mouse lung tissue,Mouse kidney tissueAll lanes: Gcgr antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 55 kDaObserved band size: 55 kDa)
Rabbit anti-Human, Mouse GCGR Polyclonal Antibody | anti-GCGR antibody
GCGR Antibody
IHC: 1:20-1:200
IF: 1:50-1:200
Western Blot (WB)
(Western BlotPositive WB detected in:Mouse heart tissue,Mouse lung tissue,Mouse kidney tissueAll lanes: Gcgr antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 55 kDaObserved band size: 55 kDa)
Western Blot (WB)
(Western BlotPositive WB detected in:Mouse heart tissue,Mouse lung tissue,Mouse kidney tissueAll lanes: Gcgr antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 55 kDaObserved band size: 55 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver tissue using MBS7048237 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver tissue using MBS7048237 at dilution of 1:100)
Immunofluorescent (IF)
(Immunofluorescent analysis of HepG2 cells using MBS7048237 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescent (IF)
(Immunofluorescent analysis of HepG2 cells using MBS7048237 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]
Uniprot Description
GCGR: This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family.
Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 17q25
Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: glucagon receptor activity; guanyl-nucleotide exchange factor activity
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; generation of precursor metabolites and energy; glucose homeostasis; regulation of blood pressure; response to nutrient; response to starvation
Disease: Diabetes Mellitus, Noninsulin-dependent
Research Articles on GCGR
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Product Notes
The GCGR gcgr (Catalog #AAA7048237) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GCGR Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GCGR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:5000 IHC: 1:20-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the GCGR gcgr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GCGR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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