Western Blot (WB)
(Western blotAll lanes: GCC1 antibody at 2ug/mlLane 1:Hela cellsLane 2:293T cellsSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 88kDaObserved band size: 88kDa)
Rabbit anti-Human GCC1 Polyclonal Antibody | anti-GCC1 antibody
GCC1 Antibody
Gene Names
GCC1; GCC1P; GCC88
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
GCC1; Polyclonal Antibody; GCC1 Antibody; GRIP and coiled-coil domain-containing protein 1; Golgi coiled-coil protein 1; anti-GCC1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Sequence Length
775
Applicable Applications for anti-GCC1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1: 500-2000
IHC: 1: 20-1: 200
IHC: 1: 20-1: 200
Immunogen
Recombinant human GRIP and coiled-coil domain-containing protein 1 protein (4-775AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162848 / sc-162850
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Western Blot (WB)
(Western blotAll lanes: GCC1 antibody at 2ug/mlLane 1:Hela cellsLane 2:293T cellsSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 88kDaObserved band size: 88kDa)
Western Blot (WB)
(Western blotAll lanes: GCC1 antibody at 2ug/mlLane 1:Hela cellsLane 2:293T cellsSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 88kDaObserved band size: 88kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7050891 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7050891 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human breast cancer using MBS7050891 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human breast cancer using MBS7050891 at dilution 1:100)
Related Product Information for anti-GCC1 antibody
Probably involved in maintaining Golgi structure.
References
[1]"Complete sequencing and characterization of 21, 243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36: 40-45(2004). [2]"A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins."Kjer-Nielsen L., Teasdale R.D., van Vliet C., Gleeson P.A. Curr. Biol. 9: 385-388(1999). [3]"GRIP domain-mediated targeting of two new coiled-coil proteins, GCC88 and GCC185, to subcompartments of the trans-Golgi network."Luke M.R., Kjer-Nielsen L., Brown D.L., Stow J.L., Gleeson P.A.J. Biol. Chem. 278: 4216-4226(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
87,811 Da
NCBI Official Full Name
GRIP and coiled-coil domain-containing protein 1
NCBI Official Synonym Full Names
GRIP and coiled-coil domain containing 1
NCBI Official Symbol
GCC1
NCBI Official Synonym Symbols
GCC1P; GCC88
NCBI Protein Information
GRIP and coiled-coil domain-containing protein 1
UniProt Protein Name
GRIP and coiled-coil domain-containing protein 1
Protein Family
UniProt Gene Name
GCC1
UniProt Entry Name
GCC1_HUMAN
NCBI Description
The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq, Jul 2008]
Uniprot Description
GCC1: Probably involved in maintaining Golgi structure.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 7q32.1
Cellular Component: cytoplasm; cytosol; Golgi apparatus; plasma membrane
Molecular Function: protein binding
Research Articles on GCC1
Similar Products
Product Notes
The GCC1 gcc1 (Catalog #AAA7050891) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GCC1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GCC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1: 500-2000 IHC: 1: 20-1: 200. Researchers should empirically determine the suitability of the GCC1 gcc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GCC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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