Rabbit anti-Human GBP6 Polyclonal Antibody | anti-GBP6 antibody

Rabbit Polyclonal to Human GBP6

Cat. Num. AAA248252

• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: GBP6; Polyclonal Antibody; Rabbit Polyclonal to Human GBP6; Anti-GBP6 Antibody (C-Terminus) IHC-plus; GBP-6; GTP-binding protein 6; Guanylate-binding protein 6; Human GBP6; anti-GBP6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Human GBP6. GBP6 antibody is predicted to not cross-react with other GBP family members.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 633

• Applicable Applications for anti-GBP6 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (5 ug/ml), WB (0.5 - 1 ug/ml); Usage: GBP6 antibody can be used for detection of GBP6 by Western blot at 0.5-1 ug/mL.
• Target Species: Human
• Immunogen Description: A 15 amino acid peptide near the carboxy terminus of human GBP6.
• Immunogen Type: Synthetic peptide
• Immunogen: GBP6 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human GBP6.
• Antigen Modification: C-Terminus
• Preparation and Storage: Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-GBP6 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunofluorescence (IF)

(Immunofluorescence of GBP6 in HeLa cells with GBP6 antibody at 5 ug/ml.)

Immunocytochemistry (ICC)

(Immunocytochemistry of GBP6 in HeLa cells with GBP6 antibody at 2.5 ug/ml.)

Western Blot (WB)

(Western blot analysis of GBP6 in HeLa cell lysate with GBP6 antibody at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide.)

Product Categories/Family for anti-GBP6 antibody

Family: New

NCBI and Uniprot Product Information

• NCBI GI #: 157671915
• NCBI GeneID: 163351
• NCBI Accession #: NP_940862.2
• NCBI GenBank Nucleotide #: NM_198460.2
• UniProt Accession #: Q6ZN66; Q6ZN86; Q7Z3F0; A2RRM3
• Molecular Weight: 34,494 Da
• NCBI Official Full Name: guanylate-binding protein 6
• NCBI Official Synonym Full Names: guanylate binding protein family, member 6
• NCBI Official Symbol: GBP6
• NCBI Protein Information: guanylate-binding protein 6; GBP-6; GTP-binding protein 6; guanine nucleotide-binding protein 6
• UniProt Protein Name: Guanylate-binding protein 6
• Protein Family: Guanylate-binding protein
• UniProt Gene Name: GBP6
• UniProt Synonym Gene Names: GBP-6
• UniProt Entry Name: GBP6_HUMAN

NCBI Description

Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).[supplied by OMIM, Dec 2008]

Uniprot Description

GBP6: Binds GTP, GDP and GMP. Belongs to the GBP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase

Chromosomal Location of Human Ortholog: 1p22.2

Molecular Function: GTPase activity; GTP binding

Biological Process: metabolic process; defense response to bacterium; immune response