Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lung tissue using at dilution of 1:100.)
Rabbit anti-Human Gastric intrinsic factor Polyclonal Antibody | anti-GIF antibody
Gastric intrinsic factor Polyclonal Antibody
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lung tissue using at dilution of 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lung tissue using at dilution of 1:100.)
NCBI and Uniprot Product Information
Uniprot Description
GIF: Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis. Defects in GIF are the cause of hereditary intrinsic factor deficiency (IFD); also known as congenital pernicious anemia. IFD is an autosomal recessive disorder characterized by megaloblastic anemia. Belongs to the eukaryotic cobalamin transport proteins family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: apical plasma membrane; endosome; extracellular region; extracellular space; lysosomal lumen; microvillus
Molecular Function: cobalamin binding
Biological Process: cobalamin metabolic process; cobalamin transport
Disease: Intrinsic Factor Deficiency
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Product Notes
The GIF gif (Catalog #AAA9415664) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Gastric intrinsic factor Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Gastric intrinsic factor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the GIF gif for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Gastric intrinsic factor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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