Western Blot (WB)
(Western blot analysis of GASR expression in A431 whole cell lysate,The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human GASR Polyclonal Antibody | anti-GASR antibody
GASR Antibody
Western Blot (WB)
(Western blot analysis of GASR expression in A431 whole cell lysate,The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of GASR expression in A431 whole cell lysate,The lane on the left is treated with the antigen-specific peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]
Uniprot Description
CCKBR: Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: 1-phosphatidylinositol-3-kinase regulator activity; cholecystokinin receptor activity; gastrin receptor activity; phosphoinositide phospholipase C activity; protein binding; type B gastrin/cholecystokinin receptor binding
Biological Process: cell proliferation; digestion; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of cell proliferation; sensory perception
Research Articles on GASR
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Product Notes
The GASR cckbr (Catalog #AAA9418353) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GASR Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GASR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-1:2000. Researchers should empirically determine the suitability of the GASR cckbr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GASR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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