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SDS-Page (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: SKOV3 and 293T cell lysates, Primary antibody:GAN Antibody at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds)

Rabbit anti-Human, Mouse GAN Polyclonal Antibody | anti-GAN antibody

GAN Antibody

Gene Names
GAN; GAN1; KLHL16
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
GAN; Polyclonal Antibody; GAN Antibody; GAN1; KLHL16; anti-GAN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen affinity purification
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.2mg/mL (varies by lot)
Applicable Applications for anti-GAN antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:200-1:400
Immunogen
Fusion protein of human GAN
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C for 1 year.

SDS-Page

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: SKOV3 and 293T cell lysates, Primary antibody:GAN Antibody at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds)

SDS-Page (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: SKOV3 and 293T cell lysates, Primary antibody:GAN Antibody at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using (GAN Antibody) at dilution 1/170.)

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using (GAN Antibody) at dilution 1/170.)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (GAN Antibody) at dilution 1/170.)

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (GAN Antibody) at dilution 1/170.)
Related Product Information for anti-GAN antibody
This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq, Oct 2008]
Product Categories/Family for anti-GAN antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
67,638 Da
NCBI Official Full Name
Homo sapiens gigaxonin, mRNA
NCBI Official Synonym Full Names
gigaxonin
NCBI Official Symbol
GAN
NCBI Official Synonym Symbols
GAN1; KLHL16
NCBI Protein Information
gigaxonin
UniProt Protein Name
Trophinin
Protein Family
UniProt Gene Name
TRO
UniProt Synonym Gene Names
KIAA1114; MAGED3
UniProt Entry Name
TROP_HUMAN

NCBI Description

This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq, Oct 2008]

Uniprot Description

TRO: Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: Xp11.22-p11.21

Cellular Component: cytoplasm; integral to plasma membrane; nucleus; plasma membrane

Molecular Function: protein binding

Biological Process: embryo implantation; homophilic cell adhesion; negative regulation of cell growth

Research Articles on GAN

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Product Notes

The GAN tro (Catalog #AAA9434840) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GAN Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GAN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:200-1:400. Researchers should empirically determine the suitability of the GAN tro for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GAN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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