Western Blot (WB)
(Western Blot: Sample: Recombinant GAL9, Human.)
Rabbit anti-Human Galectin 9 Polyclonal Antibody | anti-GAL9 antibody
Polyclonal Antibody to Galectin 9 (GAL9)
Immunohistochemistry: 5-20 ug/mL;1:50-200
Immunocytochemistry: 5-20 ug/mL;1:50-200
Optimal working dilutions must be determined by end user.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Recombinant GAL9, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant GAL9, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Tissue))
NCBI and Uniprot Product Information
NCBI Description
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: cytoplasm; cytosol; extracellular exosome; extracellular space; intracellular; nucleus
Molecular Function: carbohydrate binding; disaccharide binding; enzyme binding; galactose binding; signal transducer activity
Biological Process: cellular response to interferon-gamma; chemotaxis; ERK1 and ERK2 cascade; female pregnancy; inflammatory response; maternal process involved in female pregnancy; natural killer cell tolerance induction; negative regulation of activated T cell proliferation; negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of chemokine production; negative regulation of gene expression; negative regulation of interferon-gamma production; negative regulation of mast cell degranulation; negative regulation of natural killer cell mediated cytotoxicity; negative regulation of tumor necrosis factor production; p38MAPK cascade; positive regulation of CD4-positive, alpha-beta T cell proliferation; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; positive regulation of dendritic cell apoptotic process; positive regulation of dendritic cell chemotaxis; positive regulation of dendritic cell differentiation; positive regulation of ERK1 and ERK2 cascade; positive regulation of gene expression; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of interferon-gamma secretion; positive regulation of interleukin-1 beta secretion; positive regulation of interleukin-10 secretion; positive regulation of interleukin-12 secretion; positive regulation of interleukin-13 secretion; positive regulation of interleukin-4 production; positive regulation of interleukin-6 secretion; positive regulation of interleukin-8 secretion; positive regulation of monocyte chemotactic protein-1 production; positive regulation of NF-kappaB import into nucleus; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; positive regulation of transforming growth factor beta production; positive regulation of tumor necrosis factor secretion; positive regulation of virion penetration into host cell; regulation of interleukin-4 production; regulation of interleukin-5 production; regulation of p38MAPK cascade; response to lipopolysaccharide; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway
Research Articles on GAL9
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Product Notes
The GAL9 lgals9 (Catalog #AAA2027237) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Galectin 9 (GAL9) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Galectin 9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB),Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Western blotting: 0.5-2 ug/mL;1:500-2000 Immunohistochemistry: 5-20 ug/mL;1:50-200 Immunocytochemistry: 5-20 ug/mL;1:50-200 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the GAL9 lgals9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Galectin 9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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