Western Blot (WB)
(Western blot analysis of extracts from mouse brain cells, using GAD1/2 antibody.)
Rabbit anti-Human, Mouse GAD1/2 Polyclonal Antibody | anti-GAD1/2 antibody
GAD1/2 Antibody
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
GAD1/2; Polyclonal Antibody; GAD1/2 Antibody; Glutamate decarboxylase 2; EC 4.1.1.15; Glutamate decarboxylase 65 kDa isoform; GAD-65; 65 kDa glutamic acid decarboxylase; anti-GAD1/2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total GAD1/GAD2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
192
Applicable Applications for anti-GAD1/2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunohistochemistry: 1:50~1:100
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from human GAD1/GAD2.
Target Name
GAD1/2
Preparation and Storage
Store at -20 degree C
Western Blot (WB)
(Western blot analysis of extracts from mouse brain cells, using GAD1/2 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from mouse brain cells, using GAD1/2 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using GAD1/2 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using GAD1/2 antibody.)
Related Product Information for anti-GAD1/2 antibody
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.JB Travers, Chem Senses, Feb 2007; 32: 129 - 137.Rita Sulahian, Nucleic Acids Res., Mar 2006; 34: 1351 - 1357.Andrea Pillai, Development, Jan 2007; 134: 357 - 366.Dmytro P. Yevtushenko, J. Exp. Bot., Aug 2003; 54: 2001 - 2002.
Product Categories/Family for anti-GAD1/2 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The GAD1/2 gad2 (Catalog #AAA9403186) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GAD1/2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GAD1/2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the GAD1/2 gad2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GAD1/2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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