Western Blot (WB)
(Western blot analysis of FUT6 Antibody (Center) in HL-60 cell line lysates (35ug/lane). FUT6 (arrow) was detected using the purified Pab.)
Rabbit anti-Human FUT6 Polyclonal Antibody | anti-FUT6 antibody
FUT6, ID (FUT6, FCT3A, Alpha-(1,3)-fucosyltransferase, Fucosyltransferase 6, Fucosyltransferase VI, Galactoside 3-L-fucosyltransferase) (APC)
FLISA: 1:1,000
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of FUT6 Antibody (Center) in HL-60 cell line lysates (35ug/lane). FUT6 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of FUT6 Antibody (Center) in HL-60 cell line lysates (35ug/lane). FUT6 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(FUT6 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FUT6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(FUT6 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FUT6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(FUT6 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(FUT6 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
FUT6: Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose to alpha-2,3 sialylated substrates. Belongs to the glycosyltransferase 10 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; EC 2.4.1.65; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: Golgi apparatus; integral to membrane
Molecular Function: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; alpha(1,3)-fucosyltransferase activity; fucosyltransferase activity
Biological Process: protein amino acid glycosylation; L-fucose catabolic process
Disease: Fucosyltransferase 6 Deficiency
Research Articles on FUT6
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Product Notes
The FUT6 fut6 (Catalog #AAA6300401) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FUT6, ID (FUT6, FCT3A, Alpha-(1,3)-fucosyltransferase, Fucosyltransferase 6, Fucosyltransferase VI, Galactoside 3-L-fucosyltransferase) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FUT6 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB). FC/FACS: 1:10-50 FLISA: 1:1,000 IHC: 1:50-100 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the FUT6 fut6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FUT6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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