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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1490168 at dilution of 1:100)

Rabbit anti-Human Fractalkine Polyclonal Antibody | anti-FKN antibody

Rabbit anti-human Fractalkine polyclonal Antibody

Gene Names
CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
Fractalkine; Polyclonal Antibody; Rabbit anti-human Fractalkine polyclonal Antibody; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1; CX3CL1; NTT; SCYD1; A-152E5.2; anti-FKN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
312
Applicable Applications for anti-FKN antibody
ELISA (EIA), Immunohistochemistry (IHC)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Fractalkine protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7225 / sc-7226 / sc-20730
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1490168 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1490168 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS1490168 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gastric cancer using MBS1490168 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of Hela cells cells using MBS1490168 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of Hela cells cells using MBS1490168 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-FKN antibody
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,203 Da
NCBI Official Full Name
fractalkine isoform 2
NCBI Official Synonym Full Names
chemokine (C-X3-C motif) ligand 1
NCBI Official Symbol
CX3CL1
NCBI Official Synonym Symbols
NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
NCBI Protein Information
fractalkine
UniProt Protein Name
Fractalkine
Protein Family
UniProt Gene Name
CX3CL1
UniProt Synonym Gene Names
FKN; NTT; SCYD1
UniProt Entry Name
X3CL1_HUMAN

Uniprot Description

CX3CL1: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Belongs to the intercrine delta family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: cell projection; cell surface; extracellular region; extracellular space; integral to membrane; perinuclear region of cytoplasm; plasma membrane

Molecular Function: CCR chemokine receptor binding; chemokine activity; protein binding; receptor binding

Biological Process: aging; angiogenesis involved in wound healing; cell adhesion; chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; leukocyte adhesive activation; leukocyte chemotaxis; lymphocyte chemotaxis; macrophage chemotaxis; microglial cell activation; monocyte chemotaxis; negative regulation of cytokine secretion; negative regulation of vasoconstriction; neutrophil chemotaxis; platelet activation; positive regulation of angiogenesis; positive regulation of calcium-independent cell-cell adhesion; positive regulation of GTPase activity; positive regulation of inflammatory response; positive regulation of neuroblast proliferation; positive regulation of smooth muscle cell proliferation; positive regulation of transforming growth factor-beta1 production; regulation of inhibitory postsynaptic membrane potential; response to hypoxia

Research Articles on FKN

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Product Notes

The FKN cx3cl1 (Catalog #AAA1490168) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Fractalkine polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Fractalkine can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the FKN cx3cl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fractalkine, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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