Goat FPRL1 Polyclonal Antibody | anti-FPRL1 antibody
Goat anti-FPRL1 (aa13-26) Antibody
Gene Names
FPR2; ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
Reactivity
Expected from sequence similarity: Human
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
FPRL1; Polyclonal Antibody; Goat anti-FPRL1 (aa13-26) Antibody; Goat Anti-FPRL1 (aa328-339) Antibody; formyl peptide receptor-like 1; ALXR; FMLP-R-II; FMLPX; FPR2A; FPRH1; FPRH2; HM63; LXA4R; lipoxin A4 receptor (formyl peptide receptor related); FPRL1 antibody; formyl peptide receptor-like 1 antibody; ALXR antibody; FMLP-R-II antibody; FMLPX antibody; FPR2A antibody; FPRH1 antibody; FPRH2 antibody; HM63 antibody; LXA4R antibody; lipoxin A4 receptor (formyl peptide receptor related) antibody; FPRL1 (aa13-26); anti-FPRL1 antibody
Host
Goat
Reactivity
Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
EEVSYESAGYTVLR
Sequence Length
351
Applicable Applications for anti-FPRL1 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments gave an approx. 49kDa band in Human Peripheral Blood Mononucleocytes, and Cell line U93l7 lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 39. 0kDa according to NP_001453.1. The 49kDa band was successfully blocked by incubation with the immunizing peptide.
Western Blot: Preliminary experiments gave an approx. 49kDa band in Human Peripheral Blood Mononucleocytes, and Cell line U93l7 lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 39. 0kDa according to NP_001453.1. The 49kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence EEVSYESAGYTVLR-C, from the N Terminus of the protein sequence according to NP_001453.1.
Epitope
N Terminus
Note
Reported variants represent identical protein: NP_001005738.1 and NP_001453.1.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,964 Da
NCBI Official Full Name
N-formyl peptide receptor 2
NCBI Official Synonym Full Names
formyl peptide receptor 2
NCBI Official Symbol
FPR2
NCBI Official Synonym Symbols
ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
NCBI Protein Information
N-formyl peptide receptor 2
UniProt Protein Name
N-formyl peptide receptor 2
Protein Family
UniProt Gene Name
FPR2
UniProt Synonym Gene Names
FPRH1; FPRL1; LXA4R; FMLP-R-I; LXA4 receptor
UniProt Entry Name
FPR2_HUMAN
Uniprot Description
FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Receptor, GPCR; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19q13.3-q13.4
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activity
Biological Process: cell adhesion; cell motility; chemotaxis; G-protein coupled receptor protein signaling pathway; inflammatory response
Research Articles on FPRL1
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Product Notes
The FPRL1 fpr2 (Catalog #AAA420562) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-FPRL1 (aa13-26) Antibody reacts with Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's FPRL1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Preliminary experiments gave an approx. 49kDa band in Human Peripheral Blood Mononucleocytes, and Cell line U93l7 lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 39. 0kDa according to NP_001453.1. The 49kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the FPRL1 fpr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EEVSYESAGY TVLR. It is sometimes possible for the material contained within the vial of "FPRL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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