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Western Blot (WB) (Western blotAll lanes: FOXRED1 antibody at 5.8 ug/mlLane 1: A549 whole cell lysateLane 2: A431 whole cell lysateLane 3: Jurkat whole cell lysateLane 4: Hela whole cell lysateLane 5: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 54,31,53 kDaObserved band size: 54 kDa)

Rabbit anti-Human FOXRED1 Polyclonal Antibody | anti-FOXRED1 antibody

FOXRED1 Antibody

Gene Names
FOXRED1; H17; FP634
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
FOXRED1; Polyclonal Antibody; FOXRED1 Antibody; FAD-dependent oxidoreductase domain-containing protein 1Imported; anti-FOXRED1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
486
Applicable Applications for anti-FOXRED1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human FAD-dependent oxidoreductase domain-containing protein 1 protein (C-180AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-138281 / sc-138282 / sc-138283
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: FOXRED1 antibody at 5.8 ug/mlLane 1: A549 whole cell lysateLane 2: A431 whole cell lysateLane 3: Jurkat whole cell lysateLane 4: Hela whole cell lysateLane 5: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 54,31,53 kDaObserved band size: 54 kDa)

Western Blot (WB) (Western blotAll lanes: FOXRED1 antibody at 5.8 ug/mlLane 1: A549 whole cell lysateLane 2: A431 whole cell lysateLane 3: Jurkat whole cell lysateLane 4: Hela whole cell lysateLane 5: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 54,31,53 kDaObserved band size: 54 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045188 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045188 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7045188 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7045188 at dilution of 1:100)
Related Product Information for anti-FOXRED1 antibody
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) (PubMed:20858599, PubMed:25678554). Involved in mid-late stages of complex I assembly (PubMed:25678554).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,104 Da
NCBI Official Full Name
FAD-dependent oxidoreductase domain-containing protein 1
NCBI Official Synonym Full Names
FAD dependent oxidoreductase domain containing 1
NCBI Official Symbol
FOXRED1
NCBI Official Synonym Symbols
H17; FP634
NCBI Protein Information
FAD-dependent oxidoreductase domain-containing protein 1
UniProt Protein Name
FAD-dependent oxidoreductase domain-containing protein 1
UniProt Gene Name
FOXRED1
UniProt Entry Name
FXRD1_HUMAN

NCBI Description

This gene encodes a protein that contains a FAD-dependent oxidoreductase domain. The encoded protein is localized to the mitochondria and may function as a chaperone protein required for the function of mitochondrial complex I. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

Uniprot Description

FOXRED1: Defects in FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D). A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q24.2

Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex I; mitochondrion

Biological Process: mitochondrial respiratory chain complex I assembly

Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency

Research Articles on FOXRED1

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Product Notes

The FOXRED1 foxred1 (Catalog #AAA7045188) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOXRED1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FOXRED1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the FOXRED1 foxred1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXRED1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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