Western Blot (WB)
(Western Blot analysis of FOXK1 in K562, HepG2 and Jurkat cell lysates in order using FOXK1 Rabbit pAb at dilution 1/400)
Rabbit anti-Human, Mouse FOXK1 Polyclonal Antibody | anti-FOXK1 antibody
FOXK1 Rabbit pAb
Gene Names
FOXK1; FOXK1L
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity purified
Synonyms
FOXK1; Polyclonal Antibody; FOXK1 Rabbit pAb; forkhead box K1; FOXK1L; anti-FOXK1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.5mg/ml (varies by lot)
Applicable Applications for anti-FOXK1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Synthetic peptide of human FOXK1
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western Blot analysis of FOXK1 in K562, HepG2 and Jurkat cell lysates in order using FOXK1 Rabbit pAb at dilution 1/400)
Western Blot (WB)
(Western Blot analysis of FOXK1 in K562, HepG2 and Jurkat cell lysates in order using FOXK1 Rabbit pAb at dilution 1/400)
Related Product Information for anti-FOXK1 antibody
Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Important regulatory factor of the myogenic progenitor cell population. Involved in the cell cycle process, promotes proliferation by repressing Foxo4 transcriptional activity and the cyclin-dependent kinase inhibitor, p21CIP, in the myogenic progenitor cells. Represses myogenic differentiation by inhibiting MEFC acitivity. Has a role in remodeling processes of adult muscles that occur in response to physiological stimuli. Required to correct temporal orchestration of molecular and cellular events necessary for muscle repair. Positively regulates Wnt/beta-catenin signaling by translocating DVL into the nucleus. Reduces virus replication, probably by binding the interferon stimulated response element (ISRE) to promote antiviral gene expression.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75,457 Da
NCBI Official Full Name
forkhead box protein K1
NCBI Official Synonym Full Names
forkhead box K1
NCBI Official Symbol
FOXK1
NCBI Official Synonym Symbols
FOXK1L
NCBI Protein Information
forkhead box protein K1; MNF; myocyte nuclear factor
UniProt Protein Name
Forkhead box protein K1
Protein Family
UniProt Gene Name
FOXK1
UniProt Synonym Gene Names
MNF; MNF
UniProt Entry Name
FOXK1_HUMAN
Uniprot Description
FOXK1: Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 7p22.1
Cellular Component: nucleoplasm; nucleolus; nucleus
Molecular Function: protein binding
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; muscle development; positive regulation of transcription, DNA-dependent; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; cell differentiation
Research Articles on FOXK1
Similar Products
Product Notes
The FOXK1 foxk1 (Catalog #AAA4759502) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOXK1 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FOXK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the FOXK1 foxk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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