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Western Blot (WB) (Western blot analysis of FNTB expression in K562 (A), A431 (B), Raw264.7 (C), PC12 (D) whole cell lysates.)

Rabbit FNTB Polyclonal Antibody | anti-FNTB antibody

Anti-FNTB Antibody

Reactivity
Human, Mouse, Rat, Bovine
Applications
Western Blot
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
FNTB; Polyclonal Antibody; Anti-FNTB Antibody; Protein farnesyltransferase subunit beta; FTase-beta; CAAX farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit beta; anti-FNTB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of FNTB protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
391
Applicable Applications for anti-FNTB antibody
Western Blot (WB)
Application Notes
WB (1/500 - 1/1000)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FNTB. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of FNTB expression in K562 (A), A431 (B), Raw264.7 (C), PC12 (D) whole cell lysates.)

Western Blot (WB) (Western blot analysis of FNTB expression in K562 (A), A431 (B), Raw264.7 (C), PC12 (D) whole cell lysates.)
Related Product Information for anti-FNTB antibody
Rabbit polyclonal antibody to FNTB

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,574 Da
NCBI Official Full Name
CHURC1-FNTB protein isoform 2
NCBI Official Synonym Full Names
CHURC1-FNTB readthrough
NCBI Official Symbol
CHURC1-FNTB
NCBI Protein Information
CHURC1-FNTB protein
UniProt Protein Name
Protein farnesyltransferase subunit beta
UniProt Gene Name
FNTB
UniProt Synonym Gene Names
FTase-beta
UniProt Entry Name
FNTB_HUMAN

NCBI Description

This locus represents naturally occurring read-through transcription between the neighboring CHURC1 (churchill domain containing 1) and FNTB (farnesyltransferase, CAAX box, beta) on chromosome 14. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011]

Uniprot Description

FNTB: a subunit of farnesyltransferase that is responsible for peptide-binding. Farnesyltransferase catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins.

Protein type: EC 2.5.1.58; Transferase

Chromosomal Location of Human Ortholog: 14q23.3

Cellular Component: microtubule associated complex; cytosol

Molecular Function: protein binding; farnesyltranstransferase activity; isoprenoid binding; zinc ion binding; drug binding; peptide binding; protein farnesyltransferase activity

Biological Process: rhodopsin mediated signaling; phototransduction, visible light; negative regulation of cell proliferation; positive regulation of fibroblast proliferation; protein farnesylation; regulation of rhodopsin mediated signaling; response to inorganic substance; wound healing; response to cytokine stimulus; positive regulation of cell cycle; response to organic cyclic substance; positive regulation of nitric-oxide synthase biosynthetic process

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Product Notes

The FNTB fntb (Catalog #AAA8206462) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FNTB Antibody reacts with Human, Mouse, Rat, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's FNTB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the FNTB fntb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FNTB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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