Western Blot (WB)
(Western blot analysis of FNIP2 in mouse skeletal muscle lysate with FNIP2 antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit FNIP2 Polyclonal Antibody | anti-FNIP2 antibody
FNIP2 Antibody
Gene Names
FNIP2; FNIPL; MAPO1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
FNIP2; Polyclonal Antibody; FNIP2 Antibody; Folliculin interacting protein 2; FNIPL; anti-FNIP2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1114
Applicable Applications for anti-FNIP2 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against an 18 amino acid peptide near the amino terminus of human FNIP2.
Target Name
FNIP2
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of FNIP2 in mouse skeletal muscle lysate with FNIP2 antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of FNIP2 in mouse skeletal muscle lysate with FNIP2 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-FNIP2 antibody
FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.
Product Categories/Family for anti-FNIP2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
124,860 Da
NCBI Official Full Name
folliculin-interacting protein 2
NCBI Official Synonym Full Names
folliculin interacting protein 2
NCBI Official Symbol
FNIP2
NCBI Official Synonym Symbols
FNIPL; MAPO1
NCBI Protein Information
folliculin-interacting protein 2
UniProt Protein Name
Folliculin-interacting protein 2
Protein Family
UniProt Gene Name
FNIP2
UniProt Synonym Gene Names
FNIPL; KIAA1450; MAPO1
UniProt Entry Name
FNIP2_HUMAN
Uniprot Description
FNIP2: May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. Belongs to the FNIP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 4q32.1
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; microtubule organizing center
Molecular Function: protein binding
Biological Process: regulation of protein amino acid phosphorylation; DNA damage response, signal transduction resulting in induction of apoptosis; negative regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; positive regulation of peptidyl-serine phosphorylation
Research Articles on FNIP2
Similar Products
Product Notes
The FNIP2 fnip2 (Catalog #AAA9410332) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FNIP2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FNIP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the FNIP2 fnip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FNIP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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