Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(×200))
Rabbit anti-Human, Mouse FNDC3B Polyclonal Antibody | anti-FNDC3B antibody
FNDC3B Polyclonal Antibody
Gene Names
FNDC3B; FAD104; PRO4979; YVTM2421
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
FNDC3B; Polyclonal Antibody; FNDC3B Polyclonal Antibody; DKFZp686D14170; DKFZp762K137; Factor for adipocyte differentiation 104; FAD104; Fibronectin type III domain containing 3B; FLJ23399; HCV NS5A binding protein 37; MGC10002; NS5ABP37; PRO4979; YVTM2421; anti-FNDC3B antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.8mg/mL (varies by lot)
Sequence Length
1204
Applicable Applications for anti-FNDC3B antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:30-1:150
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Full length fusion protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(×200))
Related Product Information for anti-FNDC3B antibody
Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
Product Categories/Family for anti-FNDC3B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
fibronectin type III domain-containing protein 3B
NCBI Official Synonym Full Names
fibronectin type III domain containing 3B
NCBI Official Symbol
FNDC3B
NCBI Official Synonym Symbols
FAD104; PRO4979; YVTM2421
NCBI Protein Information
fibronectin type III domain-containing protein 3B
UniProt Protein Name
Fibronectin type III domain-containing protein 3B
Protein Family
UniProt Gene Name
FNDC3B
UniProt Synonym Gene Names
FAD104; NS5ABP37
UniProt Entry Name
FND3B_HUMAN
Uniprot Description
FNDC3B: May be a positive regulator of adipogenesis. Belongs to the FNDC3 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q26.31
Cellular Component: integral to membrane
Research Articles on FNDC3B
Similar Products
Product Notes
The FNDC3B fndc3b (Catalog #AAA2562162) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FNDC3B Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FNDC3B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:30-1:150 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the FNDC3B fndc3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FNDC3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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