Rabbit FMO5 Polyclonal Antibody | anti-FMO5 antibody
FMO5
Reactivity
HumanPredicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
FMO5; Polyclonal Antibody; anti-FMO5 antibody
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
2212
Applicable Applications for anti-FMO5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
IHC: 1:100-500
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 25-208aa of human FMO5.
Cellular Localization
Microsome Membrane, Endoplasmic Reticulum Membrane
Related Product Information for anti-FMO5 antibody
Homo sapiens flavin containing monooxygenase 5 (FMO5), transcript variant 1, mRNA.
References
Ross CJ, Katzov-Eckert H, Dube MP, et al. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. Nat. Genet. 41(12):1345-1349 (2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
58KD
NCBI Official Full Name
Homo sapiens flavin containing monooxygenase 5, mRNA
NCBI Official Synonym Full Names
flavin containing dimethylaniline monoxygenase 5
NCBI Official Symbol
FMO5
NCBI Protein Information
dimethylaniline monooxygenase [N-oxide-forming] 5
Protein Family
NCBI Description
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Research Articles on FMO5
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Product Notes
The FMO5 (Catalog #AAA8561538) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FMO5 reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FMO5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-80,000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the FMO5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FMO5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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