Western Blot (WB)
(All lanes : Anti-FLOT2 Antibody (C-Term) at 1:2000 dilutionLane 1: 293 whole cell lysateLane 2: human brain lysateLane 3: Ramos whole cell lysateLane 4: NIH/3T3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit FLOT2 Polyclonal Antibody | anti-FLOT2 antibody
FLOT2 Antibody (C-Term)
Western Blot (WB)
(All lanes : Anti-FLOT2 Antibody (C-Term) at 1:2000 dilutionLane 1: 293 whole cell lysateLane 2: human brain lysateLane 3: Ramos whole cell lysateLane 4: NIH/3T3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-FLOT2 Antibody (C-Term) at 1:2000 dilutionLane 1: 293 whole cell lysateLane 2: human brain lysateLane 3: Ramos whole cell lysateLane 4: NIH/3T3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
NCBI and Uniprot Product Information
NCBI Description
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]
Uniprot Description
FLOT2: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function. Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECM29. In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes. Belongs to the band 7/mec-2 family. Flotillin subfamily.
Protein type: Cell adhesion
Chromosomal Location of Human Ortholog: 17q11-q12
Cellular Component: acrosomal membrane; apical plasma membrane; basolateral plasma membrane; caveola; cell-cell adherens junction; cortical actin cytoskeleton; cytoplasmic vesicle; endocytic vesicle; endosome; flotillin complex; focal adhesion; lamellipodium; membrane; perinuclear region of cytoplasm; plasma membrane; uropod; vesicle
Molecular Function: ionotropic glutamate receptor binding; protease binding; protein binding; protein heterodimerization activity
Biological Process: cell adhesion; epidermis development; lipid raft formation; protein stabilization; regulation of heterotypic cell-cell adhesion; regulation of myoblast differentiation; regulation of toll-like receptor 3 signaling pathway; synaptic transmission
Research Articles on FLOT2
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Product Notes
The FLOT2 flot2 (Catalog #AAA9217304) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FLOT2 Antibody (C-Term) reacts with Human, Mouse; Predicted Reactivity: Bovine, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FLOT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB:~~1:2000. Researchers should empirically determine the suitability of the FLOT2 flot2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FLOT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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