Western Blot (WB)
(FLOT1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FLOT1 antibody detected the FLOT1 protein (arrow).)
Rabbit FLOT1 Polyclonal Antibody | anti-FLOT1 antibody
FLOT1 Antibody (N-term)
Western Blot (WB)
(FLOT1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FLOT1 antibody detected the FLOT1 protein (arrow).)
Western Blot (WB)
(FLOT1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FLOT1 antibody detected the FLOT1 protein (arrow).)
involved in vesicular trafficking and signal transduction. FLOT1
encodes a caveolae-associated, integral membrane protein. The
function of flotillin 1 has not been determined. [provided by
RefSeq].
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :
Saalik, P., et al. Bioconjug. Chem. 20(5):877-887(2009)
Rajendran, L., et al. PLoS ONE 4 (12), E8290 (2009) :
Rossy, J., et al. PLoS ONE 4 (4), E5403 (2009) :
NCBI and Uniprot Product Information
NCBI Description
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
FLOT1: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECM29. Belongs to the band 7/mec-2 family. Flotillin subfamily.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: signalosome; focal adhesion; membrane; lysosomal membrane; melanosome; integral to membrane; microtubule organizing center; flotillin complex; caveola; endosome; sarcolemma; lipid raft
Molecular Function: ionotropic glutamate receptor binding; protein binding; protease binding
Biological Process: extracellular matrix disassembly; axonogenesis; regulation of Rho protein signal transduction
Research Articles on FLOT1
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Product Notes
The FLOT1 flot1 (Catalog #AAA9206112) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 104-133. The FLOT1 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse, Pig, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's FLOT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the FLOT1 flot1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FLOT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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