Rabbit FLI1 Polyclonal Antibody | anti-FLI1 antibody
FLI1 Antibody FITC
Gene Names
FLI1; EWSR2; SIC-1
Reactivity
Cat, Human, Mouse, Pig, Rat
Applications
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
FLI1; Polyclonal Antibody; FLI1 Antibody FITC; ERGB transcription factor; Ewing Sarcoma breakpoint region 2; EWSR 2; FLI 1 proto oncogene; FLI1 EWS fusion gene; FLI1 proto oncogene; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; SIC1; Transcription factor ERGB; Viral integration region FLI1 antibody; anti-FLI1 antibody
Host
Rabbit
Reactivity
Cat, Human, Mouse, Pig, Rat
Clonality
Polyclonal
Concentration
0.55-0.75 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
395
Applicable Applications for anti-FLI1 antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:10,000
Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Immunoprecipitation: 1:150
Western Blot: 1:500
Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Immunoprecipitation: 1:150
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 1-50 on human Friend Leukemia integration 1 transcription factor protein.
Immunoglobulin
IgG
Expression
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain.
Determinant
N-epitope
Molecular Function
Chromatin Binding; DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity invovled in positive regulation of transcription.
Structure
Can form homodimers or heterodimers with ETV6/TEL1.
Subcellular Location
Nucleus
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-FLI1 antibody
FITC-Conjugated Friend leukemia integration 1 transcription factor Antibody N-epitope
Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
29,084 Da
NCBI Official Full Name
FLI-1, partial
NCBI Official Synonym Full Names
Fli-1 proto-oncogene, ETS transcription factor
NCBI Official Symbol
FLI1
NCBI Official Synonym Symbols
EWSR2; SIC-1
NCBI Protein Information
Friend leukemia integration 1 transcription factor
UniProt Protein Name
Friend leukemia integration 1 transcription factor
Protein Family
UniProt Gene Name
FLI1
UniProt Entry Name
FLI1_HUMAN
NCBI Description
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Uniprot Description
Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
Research Articles on FLI1
Similar Products
Product Notes
The FLI1 fli1 (Catalog #AAA541620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FLI1 Antibody FITC reacts with Cat, Human, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FLI1 can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 Immunocytochemistry: 1:100 Immunofluorescence: 1:100 Immunohistochemistry: 1:100 Immunoprecipitation: 1:150 Western Blot: 1:500. Researchers should empirically determine the suitability of the FLI1 fli1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FLI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
