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Testing Data (Sample(30 ug whole cell lysate)A: Hep G2 B: Raji 7.5% SDS PAGEPrimary antibody diluted at 1: 1000)

Rabbit anti-Human flavin containing monooxygenase 1 Polyclonal Antibody | anti-FMO1 antibody

flavin containing monooxygenase 1 antibody

Reactivity
Human
Applications
Western Blot
Purity
Purified by antigen-affinity chromatography.
Synonyms
flavin containing monooxygenase 1; Polyclonal Antibody; flavin containing monooxygenase 1 antibody; anti-FMO1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
532
Applicable Applications for anti-FMO1 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500-1:3000
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 407 of Human FMO1
Target Name
flavin containing monooxygenase 1
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample(30 ug whole cell lysate)A: Hep G2 B: Raji 7.5% SDS PAGEPrimary antibody diluted at 1: 1000)

Testing Data (Sample(30 ug whole cell lysate)A: Hep G2 B: Raji 7.5% SDS PAGEPrimary antibody diluted at 1: 1000)
Related Product Information for anti-FMO1 antibody
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq]
Product Categories/Family for anti-FMO1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,813 Da
NCBI Official Full Name
dimethylaniline monooxygenase
NCBI Official Synonym Full Names
flavin containing monooxygenase 1
NCBI Official Symbol
FMO1
NCBI Protein Information
dimethylaniline monooxygenase [N-oxide-forming] 1
UniProt Protein Name
Dimethylaniline monooxygenase [N-oxide-forming] 1
UniProt Gene Name
FMO1
UniProt Synonym Gene Names
FMO 1
UniProt Entry Name
FMO1_HUMAN

NCBI Description

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Uniprot Description

FMO1: This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. Belongs to the FMO family.

Protein type: EC 1.14.13.8; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450

Chromosomal Location of Human Ortholog: 1q24.3

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum lumen; integral to membrane

Molecular Function: FAD binding; NADP binding; flavin-containing monooxygenase activity; monooxygenase activity

Biological Process: organic acid metabolic process; xenobiotic metabolic process; toxin metabolic process; response to lipopolysaccharide; response to osmotic stress; drug metabolic process

Research Articles on FMO1

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Product Notes

The FMO1 fmo1 (Catalog #AAA9411672) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The flavin containing monooxygenase 1 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's flavin containing monooxygenase 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500-1:3000. Researchers should empirically determine the suitability of the FMO1 fmo1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "flavin containing monooxygenase 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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