Goat FGR Polyclonal Antibody | anti-FGR antibody
GOAT ANTI FGR
Purified IgG - liquid
Western Blotting: Minimum Dilution: 0.5ug/ml; Maximum Dilution: 2ug/ml
0.5% Bovine Serum Albumin
Buffer Solution
Shelf Life: 18 months from date of despatch.
NCBI and Uniprot Product Information
Uniprot Description
FGR: a non-receptor tyrosine kinase of the Src family. Contains one SH2 and one SH3 domain. Beta 2 integrin signaling induces its c-Cbl-mediated ubiquitination in adherent neutrophils. An ortholog of v-fgr feline oncogene. Mildly amplified in hormone-resistant prostate cancer. Copy number either increased or decreased in other cancers.
Protein type: Oncoprotein; Mitochondrial; EC 2.7.10.2; Protein kinase, TK; Kinase, protein; Protein kinase, tyrosine (non-receptor); TK group; Src family
Cellular Component: extrinsic to internal side of plasma membrane; cytoskeleton; cell projection; membrane; mitochondrion; cytoplasm; mitochondrial inner membrane; plasma membrane; cytosol; actin cytoskeleton
Molecular Function: transferase activity; protein binding; phosphotyrosine binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; non-membrane spanning protein tyrosine kinase activity; kinase activity; protein kinase binding; ATP binding; protein kinase activity
Biological Process: integrin-mediated signaling pathway; peptidyl-tyrosine phosphorylation; immune system process; protein amino acid autophosphorylation; positive regulation of phosphoinositide 3-kinase activity; positive regulation of mast cell degranulation; regulation of phagocytosis; protein amino acid phosphorylation; regulation of innate immune response; regulation of cell proliferation; positive regulation of phosphoinositide 3-kinase cascade; regulation of cell shape; defense response to Gram-positive bacterium; regulation of actin cytoskeleton organization and biogenesis; innate immune response; cell differentiation; regulation of protein kinase activity; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cytokine secretion; positive regulation of cell migration
Research Articles on FGR
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Product Notes
The FGR fgr (Catalog #AAA221676) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The GOAT ANTI FGR reacts with Human (Expected from Sequence) and may cross-react with other species as described in the data sheet. AAA Biotech's FGR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: This item detects a band of approximately 55-60kDa in mouse spleen extracts. A minimum incubation time of 1 hour is recommended for this antibody. Western Blotting: Minimum Dilution: 0.5ug/ml; Maximum Dilution: 2ug/ml. Researchers should empirically determine the suitability of the FGR fgr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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