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Immunohistochemistry (IHC) (Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit FFAR2 / GPR43 Polyclonal Antibody | anti-FFAR2 antibody

Rabbit Polyclonal to Human FFAR2 / GPR43

Gene Names
FFAR2; FFA2R; GPR43
Reactivity
Gorilla, Human, Monkey
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
FFAR2 / GPR43; Polyclonal Antibody; Rabbit Polyclonal to Human FFAR2 / GPR43; Anti-FFAR2 / GPR43 Antibody (Extracellular Domain) IHC-plus; FFAR2; FFA2R; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; LSSIG; GPR43; Gpcr43; Human FFAR2; anti-FFAR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gorilla, Human, Monkey
Clonality
Polyclonal
Specificity
Human GPR43. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
330
Applicable Applications for anti-FFAR2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (5 - 10 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from 3rd extracellular domain of human GPR43. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%).
Immunogen Type
Synthetic peptide
Immunogen
FFAR2 / GPR43 antibody was raised against synthetic 17 amino acid peptide from 3rd extracellular domain of human GPR43. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%).
Antigen Modification
Extracellular Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GPR43 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-GPR43 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-FFAR2 / GPR43 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-FFAR2 / GPR43 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-FFAR2 / GPR43 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-FFAR2 / GPR43 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-FFAR2 / GPR43 antibody IHC of human lung carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-FFAR2 / GPR43 antibody IHC of human lung carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-FFAR2 antibody
GPR43 is classified as a Carboxylic Acid GPCR. The location of this receptor in the immune system is suggestive of potential roles in immune cell function and hematopoiesis.
Product Categories/Family for anti-FFAR2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,144 Da
NCBI Official Full Name
free fatty acid receptor 2
NCBI Official Synonym Full Names
free fatty acid receptor 2
NCBI Official Symbol
FFAR2
NCBI Official Synonym Symbols
FFA2R; GPR43
NCBI Protein Information
free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; free fatty acid activated receptor 2
UniProt Protein Name
Free fatty acid receptor 2
Protein Family
UniProt Gene Name
FFAR2
UniProt Synonym Gene Names
FFA2; GPCR43; GPR43
UniProt Entry Name
FFAR2_HUMAN

NCBI Description

This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009]

Uniprot Description

FFAR2: Receptor for short chain fatty acids through a G(i)- protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: cell projection; integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; lipid binding

Biological Process: fat cell differentiation; G-protein coupled receptor protein signaling pathway; sequestering of lipid; mucosal immune response; regulation of acute inflammatory response; positive regulation of cytokine production during immune response; cell surface pattern recognition receptor signaling pathway; positive regulation of acute inflammatory response to non-antigenic stimulus; glucose homeostasis; leukocyte chemotaxis during inflammatory response; positive regulation of chemokine production

Research Articles on FFAR2

Similar Products

Product Notes

The FFAR2 ffar2 (Catalog #AAA247922) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human FFAR2 / GPR43 reacts with Gorilla, Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's FFAR2 / GPR43 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (5 - 10 ug/ml). Researchers should empirically determine the suitability of the FFAR2 ffar2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FFAR2 / GPR43, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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