Western Blot (WB)
(Western blot analysis of FEM1B expression in A549 (A) whole cell lysates.)
Rabbit anti-Human FEM1B Polyclonal Antibody | anti-FEM1B antibody
Anti-FEM1B Antibody
Western Blot (WB)
(Western blot analysis of FEM1B expression in A549 (A) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of FEM1B expression in A549 (A) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. [provided by RefSeq, Aug 2013]
Uniprot Description
FEM1B: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1. Belongs to the fem-1 family.
Protein type: Cell development/differentiation; Ligase; Ubiquitin conjugating system; Apoptosis
Chromosomal Location of Human Ortholog: 15q22
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: protein binding; death receptor binding; ubiquitin-protein ligase activity
Biological Process: regulation of ubiquitin-protein ligase activity; apoptosis; protein ubiquitination
Research Articles on FEM1B
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Product Notes
The FEM1B fem1b (Catalog #AAA8306663) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FEM1B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FEM1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the FEM1B fem1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FEM1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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