Immunohistochemistry (IHC)
(Anti-FCER1G antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)
Rabbit anti-Human FCER1G Polyclonal Antibody | anti-FCER1G antibody
Rabbit Polyclonal to Human FCER1G
Immunohistochemistry (IHC)
(Anti-FCER1G antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)
Immunohistochemistry (IHC)
(Anti-FCER1G antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:75.)
Western Blot (WB)
(FCER1G Antibody (C-term) Western blot of human spleen tissue lysates (35 ug/lane). This demonstrates the FCER1G antibody detected the FCER1G protein (arrow).)
Western Blot (WB)
(FCER1G Antibody (C-term) Western blot of human spleen tissue lysates (35 ug/lane). This demonstrates the FCER1G antibody detected the FCER1G protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008]
Uniprot Description
FCER1G: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin. Belongs to the CD3Z/FCER1G family.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1q23
Cellular Component: cell surface; integral to plasma membrane; Fc-epsilon receptor I complex; plasma membrane; external side of plasma membrane
Molecular Function: protein binding; IgG binding; IgE binding; IgE receptor activity
Biological Process: integrin-mediated signaling pathway; platelet activation; neutrophil chemotaxis; positive regulation of type I hypersensitivity; antigen processing and presentation of exogenous peptide antigen via MHC class II; positive regulation of interleukin-6 production; positive regulation of type III hypersensitivity; positive regulation of mast cell degranulation; positive regulation of tumor necrosis factor production; mast cell activation; positive regulation of interleukin-10 production; neutrophil activation during immune response; serotonin secretion by platelet; negative regulation of mast cell apoptosis; positive regulation of phagocytosis; positive regulation of type IIa hypersensitivity; defense response to bacterium; antigen processing and presentation of exogenous peptide antigen via MHC class I; innate immune response; Fc receptor mediated stimulatory signaling pathway; immunoglobulin mediated immune response; positive regulation of mast cell cytokine production; phagocytosis, engulfment; blood coagulation; leukocyte migration
Research Articles on FCER1G
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Product Notes
The FCER1G fcer1g (Catalog #AAA248276) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human FCER1G reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FCER1G can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (1:75), WB (1:1000). Researchers should empirically determine the suitability of the FCER1G fcer1g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCER1G, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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